Results 171 to 180 of about 1,570,740 (185)

Noise Propagation in Transcriptional Genetic Cascades

2023
ABSTRACTCellular processes are inherently stochastic, leading to fluctuations in protein concentration quantifiable as noise in gene expression. Precise description of noise propagation in gene networks is essential for designing noise-tolerant gene circuits and understanding signal reliability in biological networks, but current models for noise ...
JD Marmolejo, JM Pedraza
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Transcription, Reverse Transcription, and Analysis of RNA Containing Artificial Genetic Components

ACS Synthetic Biology, 2014
Expanding the synthetic biology of artificially expanded genetic information systems (AEGIS) requires tools to make and analyze RNA molecules having added nucleotide "letters". We report here the development of T7 RNA polymerase and reverse transcriptase to catalyze transcription and reverse transcription of xNA (DNA or RNA) having two complementary ...
Nicole A, Leal, Hyo-Joong, Kim, Shuichi, Hoshika, Myong-Jung, Kim, Matthew A, Carrigan, Steven A, Benner   +5 more
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Model genetic circuits encoding autoregulatory transcription factors

Journal of Theoretical Biology, 1995
Multiple steady-state levels of autoregulatory transcription factors are capable of specifying alternative heritable phenotypes of a cell or an organism. Switching among steady states can result in long-term phenotypic change. In this paper, six model genetic circuits are presented, each encoding a set of autoregulatory transcription factors.
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[Transcriptional abnormalities and genetic testing].

Medecine sciences : M/S, 2005
There is a rapidly growing literature on transcription abnormalities, e.g. differential expression of alleles and the role of some single nucleotide polymorphisms in altering splicing patterns. An average 10% of splicing mutations is reported in the Human Gene Mutation Database but this figure could climb to 50% for some genes such as NF1 or ATM.
Claude, Houdayer, Dominique, Stoppa-Lyonnet   +1 more
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Chemical-genetics refines transcription factor regulatory circuits

Trends in Cancer
Transcriptional dysregulation is a key step in oncogenesis, but our understanding of transcriptional control has relied on genetic approaches that are slow and allow for compensation. Chemical-genetic approaches have shortened the time frame for the analysis of transcription factors from days or weeks to minutes.
Hillary M. Layden, Anna E. Johnson, Scott W. Hiebert   +2 more
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Studies on Genetic Transcription

Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite Naturwissenschaftliche Abteilung: Allgemeine, Landwirtschaftliche und Technische Mikrobiologie, 1975
R.K. Kakkar, B.R. Mehrotra
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Genetics of Transcription Factor Mutations

2007
Vijaya Ramachandran, D. Woodrow Benson
openaire   +1 more source

Transcription and the genetic code

1991
C. A. Smith, E. J. Wood
openaire   +1 more source

Diversity of regulation of genetic transcription

Journal of Molecular Biology, 1974
Takashi Segawa, Fumio Imamoto
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Transcription of the Genetic Message

1974
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