Results 21 to 30 of about 1,088,355 (314)

Transcription factor competition facilitates self-sustained oscillations in single gene genetic circuits.

PLoS Computational Biology, 2023
Genetic feedback loops can be used by cells to regulate internal processes or to keep track of time. It is often thought that, for a genetic circuit to display self-sustained oscillations, a degree of cooperativity is needed in the binding and unbinding ...
Jasper Landman, Sjoerd M Verduyn Lunel, Willem K Kegel   +2 more
doaj   +1 more source

Visual analysis for drum sequence transcription [PDF]

, 2007
A system is presented for analysing drum performance video sequences. A novel ellipse detection algorithm is introduced that automatically locates drum tops.
McGuinness, Kevin, O''Connor, Noel E., O'Connor, Noel E., Gillet, Olivier, O\u27Connor, Noel E., Richard, Gaël   +5 more
core   +1 more source

Disease-associated genetic variants in the regulatory regions of human genes: mechanisms of action on transcription and genomic resources for dissecting these mechanisms

Вавиловский журнал генетики и селекции, 2021
Whole genome and whole exome sequencing technologies play a very important role in the studies of the genetic aspects of the pathogenesis of various diseases.
E. V. Ignatieva, E. A. Matrosova
doaj   +1 more source

The Network of Replication, Transcription, and Reverse Transcription of a Synthetic Genetic Cassette [PDF]

Angewandte Chemie, 2020
AbstractSynthetic nucleic acids, with four non‐canonical nucleobases, can function as genetic materials. A comprehensive analysis of PCR amplification, transcription, reverse transcription, and cloning was done to screen for alternative genetic monomers.
Yang, Hui, Eremeeva, Elena, Abramov, Mikhail, Herdewijn, Piet   +3 more
openaire   +4 more sources

Bayesian model-based inference of transcription factor activity [PDF]

, 2007
<b>Background:</b> In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is considered to be an accurate surrogate for the true ...
Rogers, S, Girolami, M, Rogers, Simon, Girolami, Mark, Khanin, R, Khanin, Raya   +5 more
core   +1 more source

Functional analysis of the competence transcription factor ComK of Bacillus subtilis by characterization of truncation variants [PDF]

, 2005
The competence transcription factor ComK is the master regulator of competence development in Bacillus subtilis. In the regulatory pathway, ComK is involved in different interactions: (i) protein–DNA interactions to stimulate transcription of ComK ...
Andy-Mark W. H. Thunnissen, Thunnissen, Andy-Mark W.H.,, Thunnissen, A.M.W.H.; id_orcid, Oscar P. Kuipers, Fusetti, F., Fabrizia Fusetti, Hamoen, L.W, Susanna, Kim, Kim A. Susanna, Susanna, Kim Amé,, Kuipers, Oscar P.,, Susanna, Kim A.,, Fusetti, Fabrizia,, Kuipers, O.P., Hamoen, Leendert W.,, Susanna, Kim Amé, Kuipers, O.P.; id_orcid, Thunnissen, A.M.W.H., Leendert W. Hamoen   +18 more
core   +1 more source

Comparación de los perfiles de transcripción de pacientes con fiebre de dengue y fiebre hemorrágica por dengue que muestra diferencias en la respuesta inmunitaria y claves en la inmunopatogénesis

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. El dengue puede manifestarse como una enfermedad leve o evolucionar hasta una enfermedad grave, llamada fiebre hemorrágica por dengue, cuyos mecanismos de inmunopatogénesis no son claros. Objetivo. Utilizar un análisis de microarreglos para
Natalia Houghton-Triviño, Katherine Martín, Kris Giaya, Jairo A. Rodríguez, Irene Bosch, Jaime E. Castellanos   +5 more
doaj   +1 more source

Genetic Variation and the Control of Transcription

Cold Spring Harbor Symposia on Quantitative Biology, 2003
Identifying and understanding genetic variation is akey driver of agricultural, biotechnological, and biomedical research and commercialization; the major focus ofgenetic variation research has until now been on changesto protein-coding sequences because these are computationally and experimentally accessible.
Cotsapas, Chris, Chan, Eva, Kirk, Michael, Tanaka, Mark, Little, Peter   +4 more
openaire   +2 more sources

Genetic and Transcriptional Control of Bone Formation [PDF]

Oral and Maxillofacial Surgery Clinics of North America, 2010
An exquisite interplay of developmental cues, transcription factors, and coregulatory and signaling proteins support formation of skeletal elements of the jaw during embryogenesis and dynamic remodeling of alveolar bone in postnatal life. These molecules promote initial condensation of the mesenchyme, commitment of the mesenchymal progenitor to ...
Amjad, Javed, Haiyan, Chen, Farah Y, Ghori   +2 more
openaire   +2 more sources

Fractional dynamics of globally slow transcription and its impact on deterministic genetic oscillation. [PDF]

PLoS ONE, 2012
In dynamical systems theory, a system which can be described by differential equations is called a continuous dynamical system. In studies on genetic oscillation, most deterministic models at early stage are usually built on ordinary differential ...
Kun Wei, Shilong Gao, Suchuan Zhong, Hong Ma   +3 more
doaj   +1 more source