Results 21 to 30 of about 1,566,033 (293)
Вавиловский журнал генетики и селекции, 2021 Whole genome and whole exome sequencing technologies play a very important role in the studies of the genetic aspects of the pathogenesis of various diseases.
E. V. Ignatieva, E. A. Matrosova
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Transcription as a Threat to Genome Integrity [PDF]
, 2016 Genomes undergo different types of sporadic alterations, including DNA damage, point mutations, and genome rearrangements, that constitute the basis for evolution.
Aguilera López, Andrés +1 more
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Oscillations in the expression of a self-repressed gene induced by a slow transcriptional dynamics [PDF]
, 2009 We revisit the dynamics of a gene repressed by its own protein in the case where the transcription rate does not adapt instantaneously to protein concentration but is a dynamical variable.
Pierre-Emmanuel Morant +8 more
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APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. [PDF]
, 2017 APETALA2 (AP2) is best known for its function in the outer two floral whorls, where it specifies the identities of sepals and petals by restricting the expression of AGAMOUS (AG) to the inner two whorls in Arabidopsis thaliana.
Chen, Xuemei +8 more
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Optogenetics for transcriptional programming and genetic engineering
Trends in Genetics, 2022 Optogenetics combines genetics and biophotonics to enable noninvasive control of biological processes with high spatiotemporal precision. When engineered into protein machineries that govern the cellular information flow as depicted in the central dogma, multiple genetically encoded non-opsin photosensory modules have been harnessed to modulate gene ...
Tien-Hung Lan +3 more
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Biomédica: revista del Instituto Nacional de Salud, 2010 Introducción. El dengue puede manifestarse como una enfermedad leve o evolucionar hasta una enfermedad grave, llamada fiebre hemorrágica por dengue, cuyos mecanismos de inmunopatogénesis no son claros. Objetivo. Utilizar un análisis de microarreglos para
Natalia Houghton-Triviño +5 more
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Transcriptional adaptation: a mechanism underlying genetic robustness [PDF]
Development, 2020 ABSTRACT Mutations play a crucial role in evolution as they provide the genetic variation that allows evolutionary change. Although some mutations in regulatory elements or coding regions can be beneficial, a large number of them disrupt gene function and reduce fitness. Organisms utilize several mechanisms to compensate for the damaging
Tamar E. Sztal, Didier Y. R. Stainier
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Fractional dynamics of globally slow transcription and its impact on deterministic genetic oscillation. [PDF]
PLoS ONE, 2012 In dynamical systems theory, a system which can be described by differential equations is called a continuous dynamical system. In studies on genetic oscillation, most deterministic models at early stage are usually built on ordinary differential ...
Kun Wei +3 more
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Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]
, 1993 Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael +2 more
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