Results 11 to 20 of about 1,088,355 (314)
Scientific Reports, 2022 Herpesviruses are known to acquire several genes from their hosts during evolution. We found that a significant proportion of virus homologues encoded by HSV-1, HSV-2, EBV and KSHV and their human counterparts contain G-quadruplex motifs in their ...
Shivani Kumar +6 more
doaj +1 more source
BMC Molecular and Cell Biology, 2020 Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been
Shivani Kumar +4 more
doaj +1 more source
Genetic determinants of neuroglobin transcription [PDF]
neurogenetics, 2013 Neuroglobin (NGB) is a neuron-specific vertebrate globin shown to protect against hypoxia, ischemia, oxidative stress and the toxic effects of Amyloid-beta. Following on our and others' results highlighting the importance of NGB expression in disease, we searched for genetic determinants of its expression.
R, Wang +4 more
openaire +2 more sources
Heliyon, 2023 Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer and accounts for about 95% of all head and neck cancers with high mortality, usually at a late stage.
Bolaji Fatai Oyeyemi +6 more
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2022 Background Salmonella belongs to the Enterobacteriaceae family, a gram-negative, non-spore-forming, rod-shaped, motile, and pathogenic bacteria that transmit through unhygienic conditions.
Malaisamy Arunkumar +7 more
doaj +1 more source
Genetic Regulation of Transcription in the Endometrium in Health and Disease [PDF]
Frontiers in Reproductive Health, 2022 The endometrium is a complex and dynamic tissue essential for fertility and implicated in many reproductive disorders. The tissue consists of glandular epithelium and vascularised stroma and is unique because it is constantly shed and regrown with each menstrual cycle, generating up to 10 mm of new mucosa. Consequently, there are marked changes in cell
Mortlock, Sally +2 more
openaire +5 more sources
Transcription Factor-Based Genetic Engineering in Microalgae
Plants, 2021 Sequence-specific DNA-binding transcription factors (TFs) are key components of gene regulatory networks. Advances in high-throughput sequencing have facilitated the rapid acquisition of whole genome assembly and TF repertoires in microalgal species.
Keiichi Mochdia, Shun Tamaki
doaj +1 more source
CRISPR-Based Genetic Switches and Other Complex Circuits: Research and Application
Life, 2021 CRISPR-based enzymes have offered a unique capability to the design of genetic switches, with advantages in designability, modularity and orthogonality.
Pei Du +5 more
doaj +1 more source
Optogenetics for transcriptional programming and genetic engineering
Trends in Genetics, 2022 Optogenetics combines genetics and biophotonics to enable noninvasive control of biological processes with high spatiotemporal precision. When engineered into protein machineries that govern the cellular information flow as depicted in the central dogma, multiple genetically encoded non-opsin photosensory modules have been harnessed to modulate gene ...
Tien-Hung Lan +3 more
openaire +2 more sources
Genetics in Light of Transcriptional Adaptation
Trends in Genetics, 2020 Genetics has recently benefited from the genome engineering revolution: genes can be knocked out, knocked down, or activated more easily than ever before. This range of genetic manipulations has also provided a range of outcomes, sometimes contradictory. But how much interesting biology hides within these discrepancies?
Kontarakis, Zacharias +1 more
openaire +4 more sources