Results 41 to 50 of about 1,089,027 (314)

Transformation of Environmental Bacillus subtilis Isolates by Transiently Inducing Genetic Competence [PDF]

, 2010
Domesticated laboratory strains of Bacillus subtilis readily take up and integrate exogenous DNA. In contrast, ‘‘wild’’ ancestors or Bacillus strains recently isolated from the environment can only be genetically modified by phage transduction ...
Nijland, Reindert,, Veening, Jan Willem, Errington, Jeff,, J. Grant Burgess, Burgess, Grant J., J Grant Burgess, Burgess, J. Grant, Reindert Nijland, Veening, Jan-Willem,, Jan-Willem Veening, Nijland, Reindert, Burgess, J. Grant,, Errington, Jeff, Jeff Errington, Veening, Jan-Willem   +14 more
core   +1 more source

Dinâmica ativa em sala de aula no ensino-aprendizado da transcrição gênica em ciências da saúde

Metodologias e Aprendizado, 2020
A metodologia ativa cria um ambiente propício para que o acadêmico tenha a possibilidade de ser resolutivo frente a um desafio, gerando o perfil profissional que está em consonância com as competências gerais dos profissionais da saúde.
Adroaldo Lunardelli, Denise Greff Machado   +1 more
doaj   +1 more source

Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53 [PDF]

, 2010
Background: The availability of various "omics" datasets creates a prospect of performing the study of genome-wide genetic regulatory networks. However, one of the major challenges of using mathematical models to infer genetic regulation from microarray ...
Junbai Wang, Tian, Tianhai, Tianhai Tian, Tian, T., Wang, Junbai, Tian Tianhai, Wang Junbai, Wang, J.   +7 more
core   +1 more source

Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. [PDF]

PLoS Biology, 2008
Previous studies in Saccharomyces cerevisiae have demonstrated that cryptic promoters within coding regions activate transcription in particular mutants.
Vanessa Cheung, Gordon Chua, Nizar N Batada, Christian R Landry, Stephen W Michnick, Timothy R Hughes, Fred Winston   +6 more
doaj   +1 more source

Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the pap1 transcription factor [PDF]

, 2012
Here we report the result of a genetic screen for mutants resistant to the microtubule poison methyl benzimidazol-2-yl carbamate (MBC) that were also temperature sensitive for growth.
Caroline R. Wilkinson (117644), Itaru Samejima, Mathiassen, Søs G, Penney, M., Mary Penney (117638), McInerny Christopher J., Samejima, I., Mairi Wallace (117659), Wallace Mairi, Søs G Mathiassen, Gordon Colin, Gordon, C., Wallace, Mairi, Christopher J. McInerny (117648), Hartmann-Petersen, Rasmus, Christopher J McInerny, McInerny, C.J., McInerny, Christopher J, Mary Penney, Takashi Toda (102488), Rasmus Hartmann-Petersen (117664), Toda, Takashi, Wilkinson, Caroline, Toda, T., Mathiassen Søs G., Penney, Mary, Colin Gordon, Penney Mary, Hartmann-Petersen, R., Itaru Samejima (117642), Wilkinson, C.R., Colin Gordon (117667), Hartmann-Petersen Rasmus, Søs G. Mathiassen (117654), Samejima Itaru, Wilkinson Caroline R., Mathiassen, Søs, Wilkinson, Caroline R, Rasmus Hartmann-Petersen, McInerny, Christopher, Toda Takashi, Wallace, M., Samejima, Itaru, Gordon, Colin, Takashi Toda, Mathiassen, S.G., Caroline R Wilkinson, Mairi Wallace   +47 more
core   +1 more source

Wheat Breeding, Transcription Factories, and Genetic Interactions: New Perspectives

Frontiers in Plant Science, 2022
Epistatic interactions and negative heterosis have been shown to be associated with interchromosomal interactions in wheat. Physical gene-gene interactions between co-regulated genes clustered in “transcription factories” have been documented, and a ...
Richard B. Flavell
doaj   +1 more source

MedProDB: A database of Mediator proteins

Computational and Structural Biotechnology Journal, 2021
In the last three decades, the multi-subunit Mediator complex has emerged as the key component of transcriptional regulation of eukaryotic gene expression.
Rohan Bhardwaj, Jitendra Kumar Thakur, Shailesh Kumar   +2 more
doaj   +1 more source

Transcriptional adaptation: a mechanism underlying genetic robustness [PDF]

Development, 2020
ABSTRACT Mutations play a crucial role in evolution as they provide the genetic variation that allows evolutionary change. Although some mutations in regulatory elements or coding regions can be beneficial, a large number of them disrupt gene function and reduce fitness. Organisms utilize several mechanisms to compensate for the damaging
Tamar E. Sztal, Didier Y. R. Stainier
openaire   +2 more sources

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks [PDF]

, 2006
Baumbach J, Brinkrolf K, Czaja LF, Rahmann S, Tauch A. CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. BMC Genomics.
Baumbach Jan, Tauch Andreas, Brinkrolf, Karina, Tauch, Andreas, Brinkrolf Karina, Rahmann Sven, Czaja, Lisa F., Baumbach, Jan, Czaja Lisa F, Rahmann, Sven   +9 more
core   +2 more sources