Results 31 to 40 of about 1,089,027 (314)

Genetic Variation and the Control of Transcription

Cold Spring Harbor Symposia on Quantitative Biology, 2003
Identifying and understanding genetic variation is akey driver of agricultural, biotechnological, and biomedical research and commercialization; the major focus ofgenetic variation research has until now been on changesto protein-coding sequences because these are computationally and experimentally accessible.
Cotsapas, Chris, Chan, Eva, Kirk, Michael, Tanaka, Mark, Little, Peter   +4 more
openaire   +2 more sources

Genetic and Transcriptional Control of Bone Formation [PDF]

Oral and Maxillofacial Surgery Clinics of North America, 2010
An exquisite interplay of developmental cues, transcription factors, and coregulatory and signaling proteins support formation of skeletal elements of the jaw during embryogenesis and dynamic remodeling of alveolar bone in postnatal life. These molecules promote initial condensation of the mesenchyme, commitment of the mesenchymal progenitor to ...
Amjad, Javed, Haiyan, Chen, Farah Y, Ghori   +2 more
openaire   +2 more sources

Using temporal correlation in factor analysis for reconstructing transcription factor activities [PDF]

, 2008
Two-level gene regulatory networks consist of the transcription factors (TFs) in the top level and their regulated genes in the second level. The expression profiles of the regulated genes are the observed high-throughput data given by experiments such ...
Wernisch, Lorenz, Lorenz Wernisch, Pournara, Iosifina, Iosifina Pournara   +3 more
core   +1 more source

Fractional dynamics of globally slow transcription and its impact on deterministic genetic oscillation. [PDF]

PLoS ONE, 2012
In dynamical systems theory, a system which can be described by differential equations is called a continuous dynamical system. In studies on genetic oscillation, most deterministic models at early stage are usually built on ordinary differential ...
Kun Wei, Shilong Gao, Suchuan Zhong, Hong Ma   +3 more
doaj   +1 more source

Sequence Motifs in MADS Transcription Factors Responsible for Specificity and Diversification of Protein-Protein Interaction [PDF]

, 2010
Protein sequences encompass tertiary structures and contain information about specific molecular interactions, which in turn determine biological functions of proteins.
Angenent, G.C., Martijn Fiers, Roeland C H J van Ham, Roeland C. H. J. van Ham, Morabito Giuseppa, Ham, R.C.H.J., van, Aalt D J van Dijk, Angenent Gerco C., Immink, R.G.H., van Dijk, A.D.J., Richard G H Immink, van Dijk Aalt D. J., Morabito, G., van Ham Roeland C. H. J., Dijk, A.D.J., van, Fiers, M.A., Richard G. H. Immink, Giuseppa Morabito, van Ham, R.C.H.J., Aalt D. J. van Dijk, Immink Richard G. H., Gerco C Angenent, Gerco C. Angenent, Fiers Martijn   +23 more
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Turnover and function of DNA methylation at transcription factor binding sites [PDF]

, 2014
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core   +1 more source

Extraction and Characterization of Fucoidan Derived from Sargassum ilicifolium and Its Biomedical Potential with In Silico Molecular Docking

Applied Sciences, 2022
Fucoidan, a polymer derived from seaweed, poses a broad range of biological applications, and its potential medicinal benefits have been widely studied over the past decade.
Archana Lakshmanan, Balamuralikrishnan Balasubramanian, Viji Maluventhen, Arunkumar Malaisamy, Rathinasamy Baskaran, Wen-Chao Liu, Maruthupandian Arumugam   +6 more
doaj   +1 more source

Impact of Module-X2 and Carbohydrate Binding Module-3 on the catalytic activity of associated glycoside hydrolases towards plant biomass

Scientific Reports, 2017
Cellulolytic enzymes capable of hydrolyzing plant biomass are secreted by microbial cells specifically in response to the carbon substrate present in the environment.
Nandita Pasari, Nidhi Adlakha, Mayank Gupta, Zeenat Bashir, Girish H. Rajacharya, Garima Verma, Manoj Munde, Rakesh Bhatnagar, Syed Shams Yazdani   +8 more
doaj   +1 more source

Genetic regulation of pituitary gland development in human and mouse [PDF]

, 2009
Normal hypothalamopituitary development is closely related to that of the forebrain and is dependent upon a complex genetic cascade of transcription factors and signaling molecules that may be either intrinsic or extrinsic to the developing Rathke’s ...
Robin Lovell-Badge, Dattani, M. T., Robinson, I. C. A. F., Mehul T. Dattani, Lovell-Badge, R., Karine Rizzoti, Iain C. A. F. Robinson, Rizzoti, K., Kelberman, D., Daniel Kelberman   +9 more
core   +1 more source

Embodied Computational Evolution: Feedback Between Development and Evolution in Simulated Biorobots

Frontiers in Robotics and AI, 2021
Given that selection removes genetic variance from evolving populations, thereby reducing exploration opportunities, it is important to find mechanisms that create genetic variation without the disruption of adapted genes and genomes caused by random ...
Joshua Hawthorne-Madell, Joshua Hawthorne-Madell, Eric Aaron, Eric Aaron, Ken Livingston, Ken Livingston, John H. Long, John H. Long   +7 more
doaj   +1 more source