Results 31 to 40 of about 3,753,914 (306)

Optogenetics for transcriptional programming and genetic engineering

Trends in Genetics, 2022
Optogenetics combines genetics and biophotonics to enable noninvasive control of biological processes with high spatiotemporal precision. When engineered into protein machineries that govern the cellular information flow as depicted in the central dogma, multiple genetically encoded non-opsin photosensory modules have been harnessed to modulate gene ...
Tien-Hung Lan, Lian He, Yun Huang, Yubin Zhou   +3 more
openaire   +2 more sources

Dia2 controls transcription by mediating assembly of the RSC complex. [PDF]

, 2011
BACKGROUND: Dia2 is an F-box protein found in the budding yeast, S. cerevisiae. Together with Skp1 and Cul1, Dia2 forms the substrate-determining part of an E3 ubiquitin ligase complex, otherwise known as the SCF.
Yu Veronica P. C. C., Veronica P. C. C. Yu, Yu, VPCC, Kessler, BM, Andress Edward J., Edelmann, MJ, Benedikt M. Kessler, Holic, R, Edelmann Mariola J., Mariola J Edelmann, Edelmann, Mariola J., Kessler Benedikt M., Mariola J. Edelmann, Yu, Veronica P. C. C., Holic, Roman, Andress, Edward J., Kessler, Benedikt M., Veronica P C C Yu, Benedikt M Kessler, Holic Roman, Edward J Andress, Roman Holic, Andress, EJ, Edward J. Andress   +23 more
core   +1 more source

Disease-associated genetic variants in the regulatory regions of human genes: mechanisms of action on transcription and genomic resources for dissecting these mechanisms

Вавиловский журнал генетики и селекции, 2021
Whole genome and whole exome sequencing technologies play a very important role in the studies of the genetic aspects of the pathogenesis of various diseases.
E. V. Ignatieva, E. A. Matrosova
doaj   +1 more source

Transcription factor competition facilitates self-sustained oscillations in single gene genetic circuits.

PLoS Computational Biology, 2023
Genetic feedback loops can be used by cells to regulate internal processes or to keep track of time. It is often thought that, for a genetic circuit to display self-sustained oscillations, a degree of cooperativity is needed in the binding and unbinding ...
Jasper Landman, Sjoerd M Verduyn Lunel, Willem K Kegel   +2 more
doaj   +1 more source

Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the pap1 transcription factor [PDF]

, 2012
Here we report the result of a genetic screen for mutants resistant to the microtubule poison methyl benzimidazol-2-yl carbamate (MBC) that were also temperature sensitive for growth.
Caroline R. Wilkinson (117644), Itaru Samejima, Mathiassen, Søs G, Penney, M., Mary Penney (117638), McInerny Christopher J., Samejima, I., Mairi Wallace (117659), Wallace Mairi, Søs G Mathiassen, Gordon Colin, Gordon, C., Wallace, Mairi, Christopher J. McInerny (117648), Hartmann-Petersen, Rasmus, Christopher J McInerny, McInerny, C.J., McInerny, Christopher J, Mary Penney, Takashi Toda (102488), Rasmus Hartmann-Petersen (117664), Toda, Takashi, Wilkinson, Caroline, Toda, T., Mathiassen Søs G., Penney, Mary, Colin Gordon, Penney Mary, Hartmann-Petersen, R., Itaru Samejima (117642), Wilkinson, C.R., Colin Gordon (117667), Hartmann-Petersen Rasmus, Søs G. Mathiassen (117654), Samejima Itaru, Wilkinson Caroline R., Mathiassen, Søs, Wilkinson, Caroline R, Rasmus Hartmann-Petersen, McInerny, Christopher, Toda Takashi, Wallace, M., Samejima, Itaru, Gordon, Colin, Takashi Toda, Mathiassen, S.G., Caroline R Wilkinson, Mairi Wallace   +47 more
core   +2 more sources

The Network of Replication, Transcription, and Reverse Transcription of a Synthetic Genetic Cassette [PDF]

Angewandte Chemie, 2020
AbstractSynthetic nucleic acids, with four non‐canonical nucleobases, can function as genetic materials. A comprehensive analysis of PCR amplification, transcription, reverse transcription, and cloning was done to screen for alternative genetic monomers.
Yang, Hui, Eremeeva, Elena, Abramov, Mikhail, Herdewijn, Piet   +3 more
openaire   +4 more sources

Bayesian model-based inference of transcription factor activity [PDF]

, 2007
<b>Background:</b> In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is considered to be an accurate surrogate for the true ...
Rogers, S, Girolami, M, Rogers, Simon, Girolami, Mark, Khanin, R, Khanin, Raya   +5 more
core   +1 more source

The Fission Yeast Homeodomain Protein Yox1p Binds to MBF and Confines MBF-Dependent Cell-Cycle Transcription to G1-S via Negative Feedback [PDF]

, 2009
The regulation of the G1- to S-phase transition is critical for cell-cycle progression. This transition is driven by a transient transcriptional wave regulated by transcription factor complexes termed MBF/SBF in yeast and E2F-DP in mammals. Here we apply
Brazma Alvis, Klier, S, Codlin, S, Lackner Daniel H., Bahler, J, Alvis Brazma, Brian T Wilhelm, Robertus A M de Bruin, Sofia Aligianni, de Bruin, RAM, Daniel H Lackner, Sandra Codlin, Gabriella Rustici, Klier Steffi, Wilhelm, BT, Rustici Gabriella, Lackner, DH, Marguerat Samuel, Aligianni, S, Bähler Jürg, de Bruin, RA, Jürg Bähler, Brazma, A, Codlin Sandra, Marguerat, S, Steffi Klier, Wilhelm Brian T., Samuel Marguerat, Aligianni Sofia, de Bruin Robertus A. M., Rustici, G   +30 more
core   +1 more source

Transcription

, 2023
Transcription in Thai and ...
Wuthigrai Siriphon (14848504), Wuthigrai Siriphon   +1 more
core   +1 more source

Comparación de los perfiles de transcripción de pacientes con fiebre de dengue y fiebre hemorrágica por dengue que muestra diferencias en la respuesta inmunitaria y claves en la inmunopatogénesis

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. El dengue puede manifestarse como una enfermedad leve o evolucionar hasta una enfermedad grave, llamada fiebre hemorrágica por dengue, cuyos mecanismos de inmunopatogénesis no son claros. Objetivo. Utilizar un análisis de microarreglos para
Natalia Houghton-Triviño, Katherine Martín, Kris Giaya, Jairo A. Rodríguez, Irene Bosch, Jaime E. Castellanos   +5 more
doaj   +1 more source