Results 71 to 80 of about 1,088,355 (314)

Genetic regulation of pituitary gland development in human and mouse

, 2009
Normal hypothalamopituitary development is closely related to that of the forebrain and is dependent upon a complex genetic cascade of transcription factors and signaling molecules that may be either intrinsic or extrinsic to the developing Rathke’s ...
Robin Lovell-Badge, Dattani, M. T., Robinson, I. C. A. F., Mehul T. Dattani, Lovell-Badge, R., Karine Rizzoti, Iain C. A. F. Robinson, Rizzoti, K., Kelberman, D., Daniel Kelberman   +9 more
core   +1 more source

The RNA helicase Rm62 cooperates with SU(VAR)3-9 to re-silence active transcription in Drosophila melanogaster. [PDF]

, 2011
Gene expression is highly dynamic and many genes show a wide range in expression over several orders of magnitude. This regulation is often mediated by sequence specific transcription factors.
Bag, I., M. Janaki Ramaiah, Ramaiah, M.J., Bag, Indira, Irene Vetter, Boeke Joern, Kremmer Elisabeth, Vetter, I., Imhof Axel, Bhadra Utpal, Bhadra, U., Kremmer, E., Boeke, J., Kremmer, Elisabeth, Axel Imhof, Manika Pal-Bhadra, Boeke, Joern, Utpal Bhadra, Pal-Bhadra, Manika, Indira Bag, Vetter, Irene, Vetter Irene, M Janaki Ramaiah, Pal-Bhadra Manika, Imhof, Axel, Pal-Bhadra, M., Joern Boeke, Bhadra, Utpal, Ramaiah, M. Janaki, Imhof, A., Bag Indira, Elisabeth Kremmer, Ramaiah M. Janaki   +32 more
core   +1 more source

Transcription factor DREF regulates expression of the microRNA gene bantam in Drosophila melanogaster

Вавиловский журнал генетики и селекции
The bantam gene encodes a vital microRNA and has a complex expression pattern in various tissues at different stages of Drosophila development. This microRNA is involved in the control of normal development of the ocu lar and wing imaginal discs, the ...
M. B.  Schwartz, M. M. Prudnikova, O. V. Andreenkov, E. I. Volkova, I. F. Zhimulev, O. V. Antonenko, S.  A. Demakov   +6 more
doaj   +1 more source

FAR1-RELATED SEQUENCE (FRS) and FRS-RELATED FACTOR (FRF) Family Proteins in Arabidopsis Growth and Development

Frontiers in Plant Science, 2018
Transposable elements make important contributions to adaptation and evolution of their host genomes. The well-characterized transposase-derived transcription factor FAR-RED ELONGATED HYPOCOTYLS3 (FHY3) and its homologue FAR-RED IMPAIRED RESPONSE1 (FAR1)
Lin Ma, Lin Ma, Gang Li
doaj   +1 more source

Gender effects on autism spectrum disorder: a multi-site resting-state functional magnetic resonance imaging study of transcriptome-neuroimaging

Frontiers in Neuroscience, 2023
IntroductionThe gender disparity in autism spectrum disorder (ASD) has been one of the salient features of condition. However, its relationship between the pathogenesis and genetic transcription in patients of different genders has yet to reach a ...
Yanling Li, Rui Li, Ning Wang, Jiahe Gu, Jingjing Gao   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The function of the protein phosphatase Glc7p in transcription termination, RNA processing and transcriptional regulation of ribosomal protein genes [PDF]

, 2007
Gene transcription in general can be subdivided into three main phases: transcription initiation, elongation and termination. The enzyme that accomplishes transcription of protein coding genes, snRNAs and snoRNAs is RNA polymerase II (RNAP II).
Röck, Salome
core   +1 more source

Genetic, Epigenetic and Transcription Factors in Atrial Fibrillation

Рациональная фармакотерапия в кардиологии, 2019
Atrial fibrillation (AF) is one of the most common arrhythmia that occurs in patients with cardiovascular diseases. Congenital forms of AF are quite rare.
O. V. Sapelnikov, A. A. Kulikov, O. O. Favorova, N. A. Matveeva, D. I. Cherkashin, O. A. Nikolaeva, R. S. Akchurin   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source