Results 141 to 150 of about 3,372,915 (384)
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Non-equilibrium dynamics of gene expression and the Jarzynski equality
, 2007 In order to express specific genes at the right time, the transcription of genes is regulated by the presence and absence of transcription factor molecules.
E. Davidson +5 more
core +1 more source
mTim: Rapid and accurate transcript reconstruction from RNA-Seq data [PDF]
arXiv, 2013 Recent advances in high-throughput cDNA sequencing (RNA-Seq) technology have revolutionized transcriptome studies. A major motivation for RNA-Seq is to map the structure of expressed transcripts at nucleotide resolution. With accurate computational tools for transcript reconstruction, this technology may also become useful for genome (re-)annotation ...
arxiv
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Graux's Facsimiles of Greek Manuscripts in Spain - Fac-Similés de Manuscrits Grecs d'Espagne, gravés d'après les photographies de Charles Graux, avec transcriptions et notices par M. Albert Martin. Paris: Hachette. 1891. 25 frcs. [PDF]
, 1891 E. Maunde Thompson
openalex +1 more source
Reliable scaling of Position Weight Matrices for binding strength comparisons between transcription factors [PDF]
arXiv, 2015 Scoring DNA sequences against Position Weight Matrices (PWMs) is a widely adopted method to identify putative transcription factor binding sites. While common bioinformatics tools produce scores that can reflect the binding strength between a specific transcription factor and the DNA, these scores are not directly comparable between different ...
arxiv
Molecular Oncology, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Sur La Transcription Des Noms Étrangers Avec Les Signes De L' Japonais [PDF]
, 1907 Pietro Silvio Rivetta
openalex +1 more source
Collective Properties of a Transcription Initiation Model under Varying Environment [PDF]
arXiv, 2015 The dynamics of gene transcription is tightly regulated in eukaryotes. Recent experiments have revealed various kinds of transcriptional dynamics, such as RNA polymerase II pausing, that involves regulation at the transcription initiation stage, and the choice of different regulation pattern is closely related to the physiological functions of the ...
arxiv