Results 141 to 150 of about 3,535,290 (383)
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Crystals, 2017 The present article describes how to use the computer program BLEND to help assemble complete datasets for the solution of macromolecular structures, starting from partial or complete datasets, derived from data collection from multiple crystals.
Anastasia Mylona +6 more
doaj +1 more source
Collective Properties of a Transcription Initiation Model under Varying Environment [PDF]
arXiv, 2015 The dynamics of gene transcription is tightly regulated in eukaryotes. Recent experiments have revealed various kinds of transcriptional dynamics, such as RNA polymerase II pausing, that involves regulation at the transcription initiation stage, and the choice of different regulation pattern is closely related to the physiological functions of the ...
arxiv
Graux's Facsimiles of Greek Manuscripts in Spain - Fac-Similés de Manuscrits Grecs d'Espagne, gravés d'après les photographies de Charles Graux, avec transcriptions et notices par M. Albert Martin. Paris: Hachette. 1891. 25 frcs. [PDF]
, 1891 E. Maunde Thompson
openalex +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Developing an Analytical Method for Separating and Quantifying RNA Generated in In Vitro Transcription Reactions [PDF]
, 2015 The generation of run-off transcripts from in vitro transcription reactions is a useful technique in the study of transcription regulation. There are currently limited ways in which these run-off transcripts can be analyzed, and few that are truly ...
Wienkers, Henry
core +1 more source
Reliable scaling of Position Weight Matrices for binding strength comparisons between transcription factors [PDF]
arXiv, 2015 Scoring DNA sequences against Position Weight Matrices (PWMs) is a widely adopted method to identify putative transcription factor binding sites. While common bioinformatics tools produce scores that can reflect the binding strength between a specific transcription factor and the DNA, these scores are not directly comparable between different ...
arxiv
Sur La Transcription Des Noms Étrangers Avec Les Signes De L' Japonais [PDF]
, 1907 Pietro Silvio Rivetta
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Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source