Results 201 to 210 of about 15,248,084 (403)

Multiple hepatic trans-acting factors are required for in vitro transcription of the human alpha-1-antitrypsin gene.

, 1988
Y Li, R F Shen, S Y Tsai, Savio L.C. Woo
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter. [PDF]

, 1985
Neil G. Miyamoto, Vincent Moncollin, J.M. Egly, Pierre Chambon   +3 more
openalex   +1 more source

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

Molecular and Cellular Biology, 1996
Jo A. Forsythe, B. Jiang, N. Iyer, F. Agani, S. Leung, R. Koos, G. Semenza   +6 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Basal association of a transcription factor favors early gene expression. [PDF]

PLoS Genet
Pinheiro S, Nadal-Ribelles M, Solé C, Vincenzetti V, Dusserre Y, Posas F, Pelet S.   +6 more
europepmc   +1 more source

A 37-base pair element in the far upstream spacer region can enhance transcription of rat rDNA in vitro and can bind to the core promoter-binding factor(s)

, 1989
Lalit C. Garg, Aparna Dixit, Samson T. Jacob   +2 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Cell fate acquisition and reprogramming by the proneural transcription factor ASCL1. [PDF]

Open Biol
Lundie-Brown J, Puletti F, Philpott A, Azzarelli R.   +3 more
europepmc   +1 more source

Crosslinking of transcription factor TFIIIA to ribosomal 5S RNA fromX.laevisbytrans-diamminedichloroplatinum (II)

, 1989
Florence Baudin, Pascale Romby, Paul J. Romaniuk, Bernard Ehresmann, Chantal Ehresmann   +4 more
openalex   +2 more sources