Results 121 to 130 of about 38,959 (207)

Endothelial Transcription Factor EB Protects Against Doxorubicin-Induced Endothelial Toxicity and Cardiac Dysfunction. [PDF]

Circulation
Du W, Ringer M, Desai D, Khandakar GI, Tron Esqueda LE, Wang C, Guan JL, Becker RC, Sadayappan S, Fan GC, Wang Y, Fan Y.   +11 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

A comprehensive in silico investigation into the deleterious nonsynonymous single nucleotide polymorphisms of the human transcription factor EB (TFEB) gene and their predicted association with cancer. [PDF]

J Genet Eng Biotechnol
Fuad M, Akter S, Mahmud Z, Tamanna S, Sayem M, Islam Zim AR, Hossain Howlader MZ.   +6 more
europepmc   +1 more source

Peroxisome proliferator-activated receptor γ activation ameliorates liver fibrosis-differential action of transcription factor EB and autophagy on hepatocytes and stellate cells. [PDF]

Hepatol Commun, 2023
Yum YJ, Yoo J, Bang K, Jun JE, Jeong IK, Ahn KJ, Chung HY, Hwang YC.   +7 more
europepmc   +1 more source

Assessing and strengthening community‐based coastal governance

Conservation Biology, EarlyView.
Abstract Community‐based coastal governance is essential for biodiversity conservation and sustainable livelihoods, yet many communities continue to face significant challenges in establishing and sustaining effective governance systems. We sought to improve understanding of the current status of community‐based coastal governance across five countries
Mark Andrachuk, Graham Epstein, Shauna Mahajan, Zephania Arnold, Sinezio Junior, Dresy Lovasoa, Monalisa Mabandla, George W. Maina, Caroline Njeri, Samson Obiene, Geoffrey Odhiambo, Lenice Ojwang, Samantha Petersen, Vatosoa Rakotondrazafy, Joshua Rambahiniarison, Lilia Rasolofomanana, Tojo Rasolozaka, Maafaka Ravelona, Craig Smith, Pascal Thoya, Abel Valdivia, Milton Jose Xavier   +21 more
wiley   +1 more source

Protocol for monitoring the stability of transcription factor EB using global protein stability assay. [PDF]

STAR Protoc
Wang B, Zhao Y, Li R, Li X, Dong C, Mi W, Wang X.   +6 more
europepmc   +1 more source

Transcription factor EB coordinates environmental cues to regulate T regulatory cells' mitochondrial fitness and function. [PDF]

Proc Natl Acad Sci U S A, 2022
Xia M, Zhang C, Chen Y, Zhao X, Zhang S, Liu Y, Cai Y, Wei Z, Du Q, Yu W, Zhou C, Xiao H, Wang G, Cheng X, Mei H, Laurence A, Wang J, Hu Y, Li H, Yang XP.   +19 more
europepmc   +1 more source

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

Cell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu, Bingyu Cai, Tingting Gao, Wumei Wei, Liu Wang, Qi Zhou, Wei Li, Jie Hao, Jun Wu   +8 more
wiley   +1 more source

Tributyltin induces conjugation of ATG8s to single membranes via the V-ATPase-ATG16L1 axis, leading to transcription factor EB activation in human cell lines. [PDF]

Arch Toxicol
Hatamiya S, Miyara M, Takahashi N, Oguro A, Kotake Y.   +4 more
europepmc   +1 more source

S1 guideline sweat gland carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The current classification of sweat gland carcinomas is based on histomorphological characteristics and distinguishes between more than 20 entities. Most patients are older, but some subtypes also affect middle‐aged and younger patients. The majority of tumors arise de novo. Sweat gland carcinomas have nonspecific clinical features.
Mirjana Ziemer, Michael Erdmann, Abbas Agaimy, Jürgen C. Becker, Almut Böer‐Auer, Doris Helbig, Cornelia Erfurt‐Berge, Alexander Frisman, Conrad Hempel, Ulrike Leiter, Friedegund Meier, Thomas Mentzel, Lara Racz, Silke Redler, Stefan Schliep, Clemens Seidel, Alpaslan Tasdogan, Jochen Utikal, Carsten Weishaupt, Selma Ugurel   +19 more
wiley   +1 more source