Results 121 to 130 of about 4,631,251 (249)
Recombinant Mitochondrial Transcription Factor A with N-terminal Mitochondrial Transduction Domain Increases Respiration and Mitochondrial Gene Expression in G11778A Leber's Hereditary Optic Neuropathy Cybrid Cells [PDF]
, 2008 Diseases involving mitochondrial defects usually manifest themselves in high-energy, post-mitotic tissues such as brain, retina, skeletal and cardiac muscle and frequently cause deficiencies in mitochondrial bioenergetics.
James P. Bennett +5 more
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Journal of Applied Toxicology, EarlyView.ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari +7 more
wiley +1 more source
Can We Change? Applying Vosniadou's Theory to Assessment Reform in Dental Education
Journal of Dental Education, EarlyView.ABSTRACT Background Assessment reform in medical education is challenging, often encountering resistance from institutional norms and deeply held educator beliefs. These beliefs influence the success of reform initiatives. Sustained reform requires understanding educators’ conceptual models—how they form, persist, and transform over time—so that ...
Elvina Bonnici +2 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang +4 more
wiley +1 more source
Functional and cell-specific regulation of the Brn-3b transcription factor by microRNAs [PDF]
, 2010 Post-transcriptional gene regulation is a very powerful and evolutionary conserved mechanism which allows cells to finely modulate gene expression by acting at the level of their mRNAs.
Calissano, M.
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Knowledge and Process Management, EarlyView.ABSTRACT This study examines how knowledge management (KM) structures the dynamics of challenges and competencies associated with digital transformation within the human resources (HR) function in the context of Industry 4.0. Adopting a qualitative, exploratory, and prospective research design, the study combines the Delphi technique with ...
Celso Machado Júnior +8 more
wiley +1 more source
The post-translational regulation of transcription factor EB (TFEB) in health and disease. [PDF]
EMBO Rep, 2023 Takla M, Keshri S, Rubinsztein DC.
europepmc +1 more source
Lipids, EarlyView.The experimental design and the exometabolomic findings obtained by 1H‐NMR analysis of conditioned media from subcutaneous (SAT) and epididymal adipose tissue (EAT) explants of control and obese mice supplemented with chia oil (1.5% (w/w)). Following 8 weeks of control or high‐fat diet and 5 weeks of chia oil supplementation, SAT and EAT explants were ...
Gilson Costa dos Santos Jr +5 more
wiley +1 more source
Veterinary Research25-Hydroxycholesterol (25HC) is a hydroxylated cholesterol with multiple antiviral activities, however, little is known about the mechanisms by which 25HC correlates antiviral ability with lipid droplet (LD) dynamic balance to ensure cholesterol ...
Jia-lu Zhang +4 more
doaj +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Purpose We aimed to describe the association of lower urinary tract symptoms (LUTS) with emotional distress using questionnaires and qualitative interviews. Methods We used a convergent parallel mixed methods design to examine relationships between the LURN Symptom Index‐29 (LURN SI‐29) questionnaire and emotional distress, measured by the ...
Grace E. Bardwick +102 more
wiley +1 more source