Results 131 to 140 of about 38,959 (207)

Innovative Psychosocial Skills Training Programme for Dental Students: A Pilot Study

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Dental practice requires not only technical expertise but also well‐developed psychosocial skills (PSS), including emotional regulation, communication and empathy. Emotional intelligence (EI) plays a key role in managing complex clinical interactions and supporting both patient outcomes and practitioner well‐being. However, EI and
Anne‐Sophie Vaillant‐Corroy, Claire Egloff‐Juras, Marjorie Faure, Maxime Ducret, Imane El Baraka, Yasmina Kebir, Valérie Saint Dizier De Almeida   +6 more
wiley   +1 more source

Feasibility of transcription factor EB as a serological metric of poor prognosis following moderate-severe traumatic brain injury: A prospective cohort study. [PDF]

Medicine (Baltimore)
Zhang L, Ma H, Zhang X, Zhou Y, Shen Y, Tang H, Shao J, Zhang D.   +7 more
europepmc   +1 more source

Celastrol, a TFEB (transcription factor EB) agonist, is a promising drug candidate for Alzheimer disease. [PDF]

Autophagy, 2022
Zhang W, Wang J, Yang C.
europepmc   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

Transcription factor EB improves hypoxic pulmonary hypertension in fetal rats by suppressing NLRP3 inflammasome activation via induction of mitophagy. [PDF]

Sci Rep
Chen C, Xie Z, Ao D, Chen Y, Liu L, Li C.   +5 more
europepmc   +1 more source

Narirutin activates TFEB (transcription factor EB) to protect against Acetaminophen-induced liver injury by targeting PPP3/calcineurin. [PDF]

Autophagy, 2023
Fang Z, Xu Y, Liu G, Shao Q, Niu X, Tai W, Shen T, Fan M, Chen M, Lei L, Gao W, Song Y, Wang Z, Du X, Li X.   +14 more
europepmc   +1 more source

Dual IRE1 targets: Determinants of the cell fate?

The FEBS Journal, EarlyView.
IRE1 is an ER stress sensor that restores protein homeostasis through two signaling activities: XBP1s, which upregulates its target gene expression or RIDD which downregulates its target transcripts. We recently identified Dual IRE1 Targets (DIT) which are modulated by both XBP1s and RIDD activities.
Eva Billat, Léane Legrand, Tony Avril, Elodie Lafont   +3 more
wiley   +1 more source

Melatonin Mitigates Acidosis-Induced Neuronal Damage by Up-Regulating Autophagy via the Transcription Factor EB. [PDF]

Int J Mol Sci
Shi Y, Mi Z, Zhao W, Hu Y, Xiang H, Gan Y, Yuan S.   +6 more
europepmc   +1 more source

Stimulating proteasomal degradation in human proteinopathies

The FEBS Journal, EarlyView.
The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch, Enrica Barchi, Nico P. Dantuma   +2 more
wiley   +1 more source

Clinical improvement and scalp microbiome restructuring following a 28‐day piroctone olamine shampoo intervention

International Journal of Cosmetic Science, EarlyView.
A 28‐day clinical study in 41 individuals with oily dandruff showed that a piroctone olamine shampoo improved clinical symptoms while selectively reshaping the scalp bacterial and fungal microbiome toward a less dysbiotic profile. Abstract Objective To evaluate the clinical efficacy of a piroctone olamine–containing shampoo in individuals with oily ...
Spyridon Markos, Lina Praefke, Yiannis Kapetanstatakis, Michail Tsanakas, Evangelos Beletsiotis   +4 more
wiley   +1 more source