Results 141 to 150 of about 4,631,251 (249)
Phytotherapy Research, EarlyView.Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia +6 more
wiley +1 more source
Novel Insight into Functions of Transcription Factor EB (TFEB) in Alzheimer's Disease and Parkinson's Disease. [PDF]
Aging Dis, 2023 Yang J +6 more
europepmc +1 more source
A Triangulenum‐Based Biosensor Platform for Mapping Kinase Activity in T Cells
Small, EarlyView.Novel peptide biosensors based on long‐lifetime triangulenium dyes are developed for the real‐time, non‐invasive mapping of Akt1 and Src kinase activities in living cells. Utilizing FLIM microscopy, these highly specific, biocompatible probes overcome cellular autofluorescence.
Carmen Salto‐Giron +11 more
wiley +1 more source
Transcription Factor EB-Mediated Lysosomal Function Regulation for Determining Stem Cell Fate under Metabolic Stress. [PDF]
Mol Cells, 2023 Chae CW, Jung YH, Han HJ.
europepmc +1 more source
A photoimmune synergizing RNA interference technology for highly effective antitumor treatment
Smart Molecules, EarlyView.We developed a red‐light‐activated small‐molecule photosensitizer FNBS, which enables simultaneous photodynamic immunotherapy and RNA interference. FNBS can induce pyroptosis, immunogenic cell death and RNA degradation, avoiding the carrier‐dependent delivery drawbacks of conventional RNAi therapy, converting cold tumors into hot tumors and ...
Xiang Xia +6 more
wiley +1 more source
Small Methods, EarlyView.Nature‐inspired bi‐functionalized magnetic nanoparticles are engineered for the rapid, non‐invasive extraction of cell‐free DNA from unprocessed urine for liquid biopsy. These cationic particles leverage electrostatic interactions to outperform conventional kits, enhancing the recovery of short DNA fragments while maintaining DNA integrity.
Dina Haddad +4 more
wiley +1 more source
Transcription-Factor-Induced Aggregation of Biomimetic Oligonucleotide‑b‑Protein Micelles
Polymeric micelles and especially those based on natural diblocks are of particular interest due to their advantageous properties in terms of molecular recognition, biocompatibility, and biodegradability.
James E. Galagan (9395242) +6 more
core +1 more source
TESOL Quarterly, EarlyView.Abstract This qualitative study explores how secondary content‐area teachers of emergent bilingual (EB) students navigate tensions between linguistically responsive professional development (PD) and the implementation of state‐mandated College and Career Readiness (CCR) curricula in south Texas.
Caryn Calisi +8 more
wiley +1 more source
Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice. [PDF]
Front Cardiovasc Med, 2023 Dörmann N +16 more
europepmc +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho +7 more
wiley +1 more source