Results 161 to 170 of about 38,959 (207)

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Heterophyllin B enhances transcription factor EB-mediated autophagy and alleviates pyroptosis and oxidative stress after spinal cord injury. [PDF]

Int J Biol Sci
Zhang H, Wang W, Hu X, Wang Z, Lou J, Cui P, Zhao X, Wang Y, Chen X, Lu S.   +9 more
europepmc   +1 more source

Selective seasonal foraging behavior of herbivores on a Danish island demonstrated by DNA metabarcoding

Restoration Ecology, EarlyView.
Abstract Introduction Understanding how herbivores influence plant communities is critical for managing biodiversity and ecosystem functions, particularly in conservation areas undergoing restoration or rewilding, where free‐ranging large herbivores impact the vegetation development.
Henry F. N. Lankes, Louise I. Nabe‐Nielsen, Kristine Bohmann, Kasun H. Bodawatta, Jacob Heilmann‐Clausen   +4 more
wiley   +1 more source

Transcription factor EB reprograms branched-chain amino acid metabolism and promotes pancreatic cancer progression via transcriptional regulation of BCAT1. [PDF]

Cell Prolif
Wang T, Hu Q, Li B, Fan G, Jing D, Xu J, Hu Y, Dang Q, Ji S, Zhou C, Zhuo Q, Xu X, Qin Y, Yu X, Li Z.   +14 more
europepmc   +1 more source

Implementability of Point‐of‐Care Ultrasound for Paediatric Tuberculosis Diagnosis in Resource‐Constrained Settings: Experiences and Perspectives From Uganda

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Childhood tuberculosis (TB) remains a significant global health challenge, with a substantial number of cases going undiagnosed, particularly among children under five. Early diagnosis and intervention are crucial to reduce TB‐associated morbidity and mortality.
Julia van den Brink, Martien Humblet, Emmanuel Nasinghe, Grace Paul Kisitu, Emmanual Tenywa, Rinn Song, Nora Engel, Francesca Wanda Basile, Else Margreet Bijker   +8 more
wiley   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Correction: Zhang et al. Hepatitis B Virus X Protein (HBx) Suppresses Transcription Factor EB (TFEB) Resulting in Stabilization of Integrin Beta 1 (ITGB1) in Hepatocellular Carcinoma Cells. Cancers 2021, 13, 1181. [PDF]

Cancers (Basel)
Zhang C, Yang H, Pan L, Zhao G, Zhang R, Zhang T, Xiao Z, Tong Y, Zhang Y, Hu R, Pandol SJ, Han YP.   +11 more
europepmc   +1 more source

Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski, Phetcharawan Lye, Enrrico Bloise, Stephen G. Matthews   +3 more
wiley   +1 more source