Results 171 to 180 of about 4,631,251 (249)

A comprehensive in silico investigation into the deleterious nonsynonymous single nucleotide polymorphisms of the human transcription factor EB (TFEB) gene and their predicted association with cancer. [PDF]

J Genet Eng Biotechnol
Fuad M, Akter S, Mahmud Z, Tamanna S, Sayem M, Islam Zim AR, Hossain Howlader MZ.   +6 more
europepmc   +1 more source

Transcription factor EB coordinates environmental cues to regulate T regulatory cells' mitochondrial fitness and function. [PDF]

Proc Natl Acad Sci U S A, 2022
Xia M, Zhang C, Chen Y, Zhao X, Zhang S, Liu Y, Cai Y, Wei Z, Du Q, Yu W, Zhou C, Xiao H, Wang G, Cheng X, Mei H, Laurence A, Wang J, Hu Y, Li H, Yang XP.   +19 more
europepmc   +1 more source

‘Ambidexterity in Action’: Combining Exploitation and Exploration Through Innovation Portfolio Management for Interlinked Ambidexterity

Creativity and Innovation Management, EarlyView.
ABSTRACT Many companies face the challenge of successfully managing the tensions from simultaneously exploiting their current business for incremental innovations while exploring new opportunities for more radical innovations. Increasingly, scholars suggest ‘interlinked ambidexterity’ with successive separation and integration of exploration and ...
Lysander Weiss, Lukas Schlotfeldt
wiley   +1 more source

Tributyltin induces conjugation of ATG8s to single membranes via the V-ATPase-ATG16L1 axis, leading to transcription factor EB activation in human cell lines. [PDF]

Arch Toxicol
Hatamiya S, Miyara M, Takahashi N, Oguro A, Kotake Y.   +4 more
europepmc   +1 more source

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

Cell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu, Bingyu Cai, Tingting Gao, Wumei Wei, Liu Wang, Qi Zhou, Wei Li, Jie Hao, Jun Wu   +8 more
wiley   +1 more source

Innovative Psychosocial Skills Training Programme for Dental Students: A Pilot Study

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Dental practice requires not only technical expertise but also well‐developed psychosocial skills (PSS), including emotional regulation, communication and empathy. Emotional intelligence (EI) plays a key role in managing complex clinical interactions and supporting both patient outcomes and practitioner well‐being. However, EI and
Anne‐Sophie Vaillant‐Corroy, Claire Egloff‐Juras, Marjorie Faure, Maxime Ducret, Imane El Baraka, Yasmina Kebir, Valérie Saint Dizier De Almeida   +6 more
wiley   +1 more source

Feasibility of transcription factor EB as a serological metric of poor prognosis following moderate-severe traumatic brain injury: A prospective cohort study. [PDF]

Medicine (Baltimore)
Zhang L, Ma H, Zhang X, Zhou Y, Shen Y, Tang H, Shao J, Zhang D.   +7 more
europepmc   +1 more source

Celastrol, a TFEB (transcription factor EB) agonist, is a promising drug candidate for Alzheimer disease. [PDF]

Autophagy, 2022
Zhang W, Wang J, Yang C.
europepmc   +1 more source

Clinical improvement and scalp microbiome restructuring following a 28‐day piroctone olamine shampoo intervention

International Journal of Cosmetic Science, EarlyView.
A 28‐day clinical study in 41 individuals with oily dandruff showed that a piroctone olamine shampoo improved clinical symptoms while selectively reshaping the scalp bacterial and fungal microbiome toward a less dysbiotic profile. Abstract Objective To evaluate the clinical efficacy of a piroctone olamine–containing shampoo in individuals with oily ...
Spyridon Markos, Lina Praefke, Yiannis Kapetanstatakis, Michail Tsanakas, Evangelos Beletsiotis   +4 more
wiley   +1 more source

Transcription factor EB improves hypoxic pulmonary hypertension in fetal rats by suppressing NLRP3 inflammasome activation via induction of mitophagy. [PDF]

Sci Rep
Chen C, Xie Z, Ao D, Chen Y, Liu L, Li C.   +5 more
europepmc   +1 more source