Results 191 to 200 of about 4,631,251 (249)

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Transcription Factor EB: A Promising Therapeutic Target for Ischemic Stroke. [PDF]

Curr Neuropharmacol
Shao J, Lang Y, Ding M, Yin X, Cui L.
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Serum Transcription Factor EB Levels in Relation to Poor Neurological Prognosis and Mediation Effect of Stroke-Associated Pneumonia in Acute Intracerebral Hemorrhage: Evidence from a Two-Center Prospective Cohort Study. [PDF]

Int J Gen Med
Wang K, Zhan G, Jiang Q, Jiang C, Zheng G, Tang Z.   +5 more
europepmc   +1 more source

Implementability of Point‐of‐Care Ultrasound for Paediatric Tuberculosis Diagnosis in Resource‐Constrained Settings: Experiences and Perspectives From Uganda

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Childhood tuberculosis (TB) remains a significant global health challenge, with a substantial number of cases going undiagnosed, particularly among children under five. Early diagnosis and intervention are crucial to reduce TB‐associated morbidity and mortality.
Julia van den Brink, Martien Humblet, Emmanuel Nasinghe, Grace Paul Kisitu, Emmanual Tenywa, Rinn Song, Nora Engel, Francesca Wanda Basile, Else Margreet Bijker   +8 more
wiley   +1 more source

Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis. [PDF]

Mol Neurodegener
Ye J, Zhong S, Wan H, Guo X, Yao X, Liu Q, Chen L, Wang JZ, Xiao S.   +8 more
europepmc   +1 more source

Treatment of Canine Atopic Dermatitis: Updated Guidelines From the International Committee on Allergic Diseases of Animals (ICADA)

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a genetically, aetiologically, immunologically and clinically complex disease requiring both individualised immediate and long‐term management. Objectives These updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA) aim to substantially revise previous ...
Ralf S. Mueller, Frane Banovic, Emmanuel Bensignor, Domenico Santoro, Tim Nuttall   +4 more
wiley   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Mechanism of Huayu Qutan recipe anti-atherosclerosis mediates lipophagymammalian target of rapamycin complex 1/ transcription factor EB signaling pathway in ApoE-/-mice. [PDF]

J Tradit Chin Med
Yue LI, Jiaxiang P, Guanlin Y, Jiajia YU, Xize WU, Dongyu M, Meijia C, Dongdong YU, Minghua N, Xiaoyu G, Linlin P, Lihong G, Lianqun J.   +12 more
europepmc   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source