Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Genome-Wide Organization and Expression Profiling of the NAC Transcription Factor Family in Potato (Solanum tuberosum L.) [PDF]
, 2013 Anil Kumar Singh +4 more
openalex +1 more source
The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens [PDF]
, 2020 Lan Kang +9 more
openalex +1 more source
The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans [PDF]
, 2021 Raha Parvizi Omran +8 more
openalex +1 more source
The interaction landscape between transcription factors and the nucleosome
Nature, 2017 Nucleosomes cover most of the genome and are thought to be displaced by transcription factors in regions that direct gene expression. However, the modes of interaction between transcription factors and nucleosomal DNA remain largely unknown.
F. Zhu +11 more
semanticscholar +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Runx transcription factors in neuronal development
Neural Development, 2008 Runt-related (Runx) transcription factors control diverse aspects of embryonic development and are responsible for the pathogenesis of many human diseases. In recent years, the functions of this transcription factor family in the nervous system have just
Shiga Takashi +2 more
doaj +1 more source
A WRKY transcription factor PbrWRKY53 from Pyrus betulaefolia is involved in drought tolerance and AsA accumulation [PDF]
, 2019 Yue Liu +10 more
openalex +1 more source
Classes of fast and specific search mechanisms for proteins on DNA
, 2011 Problems of search and recognition appear over different scales in biological systems. In this review we focus on the challenges posed by interactions between proteins, in particular transcription factors, and DNA and possible mechanisms which allow for ...
Abramowitz M +32 more
core +2 more sources
Regulation of transcription factors by sumoylation
Transcription, 2017 Transcription factors (TFs) are among the most frequently detected targets of sumoylation, and effects of the modification have been studied for about 200 individual TFs to date. TF sumoylation is most often associated with reduced target gene expression,
E. Rosonina +4 more
semanticscholar +1 more source