Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
The combinatorial binding syntax of transcription factors in forebrain-specific enhancers. [PDF]
Batool F+4 more
europepmc +1 more source
Physical properties and DNA-binding stoichiometry of a 5 S gene-specific transcription factor.
James J. Bieker, Robert G. Roeder
openalex +1 more source
Transcription elongation factor SII interacts with a domain of the large subunit of human RNA polymerase II. [PDF]
Jay Rappaport+5 more
openalex +1 more source
Multidimensional regulation of transcription factors: decoding the comprehensive signals of plant secondary metabolism. [PDF]
Li H, Chen N, Zhang H, Xu D.
europepmc +1 more source
Molecular cloning and characterization of cDNA for eukaryotic transcription factor S-II.
Shoji Hirashima+3 more
openalex +1 more source
DNA unwinding ability ofXenopustranscription factor A [PDF]
Jay S. Hanas+2 more
openalex +1 more source
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang+11 more
wiley +1 more source
Characterization of the RNA binding properties of transcription factor IIIA ofXenopus laevisoocytes
Paul J. Romaniuk
openalex +2 more sources
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source