Results 101 to 110 of about 5,966,093 (336)
The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription
eLife, 2017 Cell growth requires synthesis of ribosomal RNA by RNA polymerase I (Pol I). Binding of initiation factor Rrn3 activates Pol I, fostering recruitment to ribosomal DNA promoters.
Eva Torreira +9 more
doaj +1 more source
Cell Research, 2013 Technologies allowing for specific regulation of endogenous genes are valuable for the study of gene functions and have great potential in therapeutics.
A. Cheng +9 more
semanticscholar +1 more source
Structural basis of transcription activation [PDF]
Science, 2016 Transcription activation all about timing Regulating transcription by RNA polymerase (RNAP) is central to controlling gene expression. Transcription factors influence the activity of the RNAP. Feng et al. determined the crystal structure of a bacterial transcription activation complex.
Yu, Feng, Yu, Zhang, Richard H, Ebright
openaire +2 more sources
Regulation of bistability in the std fimbrial operon of Salmonella enterica by DNA adenine methylation and transcription factors HdfR, StdE and StdF [PDF]
, 2019 Bistable expression of the Salmonella enterica std operon is controlled by an AND logic gate involving three transcriptional activators: the LysR-type factor HdfR and the StdE and StdF regulators encoded by the std operon itself.
Casadesús Pursals, Josep +4 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and Diversity
Biomolecules, 2015 Acute inflammation, an integral part of host defence and immunity, is a highly conserved cellular response to pathogens and other harmful stimuli. An inflammatory stimulation triggers transcriptional activation of selective pro-inflammatory genes that ...
Afsar U. Ahmed +2 more
doaj +1 more source
Genes & Development, 1999 Transcription factor Nrf2 is essential for the antioxidant responsive element (ARE)-mediated induction of phase II detoxifying and oxidative stress enzyme genes.
K. Itoh +7 more
semanticscholar +1 more source
One-two punch mechanism of gene repression: a fresh perspective on gene regulation. [PDF]
, 2017 Cellular differentiation depends on temporally controlled waves of gene activation and inactivation that ultimately transform one cell type into another.
Tresenrider, Amy, Ünal, Elçin
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2017 Cyclic AMP (cAMP) inducible transcription factor cAMP responsive element binding protein 3 like 1 (Creb3l1) is strongly activated in the hypothalamus in response to hyperosmotic cues such as dehydration (DH).
Michael P. Greenwood +5 more
doaj +1 more source