Results 251 to 260 of about 192,584 (302)

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

Advanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro, Aldo R. Boccaccini, Nicholas R. Forsyth, Tina P. Dale   +3 more
wiley   +1 more source

RATEX: A Scalable RNA‐Based Platform for Logical and Multi‐Layered Cellular Programming

Angewandte Chemie, EarlyView.
RATEX integrated ribosome‐mediated transcription control with synthetic RNA regulators, enabling simultaneous processing of RNA, metabolite, and small‐molecule inputs through complex logic operations within a single transcript. The platform achieves up to 1,492‐fold gene regulation, multi‐input hybrid logic gates, RNA‐programmed signaling cascades, and
Hyunseop Goh, Hansol Kang, Chaeri Kim, Jongmin Kim   +3 more
wiley   +2 more sources

Deciphering the regulatory landscape of enhancer RNAs in health and disease. [PDF]

Signal Transduct Target Ther
Wang Q, Ten Dijke P, Fan C.
europepmc   +1 more source

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

Advanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo, Simone Micalizzi, Girish Pattappa, Philipp Stahlhut, Jürgen Groll, Carmelo De Maria, Denitsa Docheva, Giovanni Vozzi   +7 more
wiley   +1 more source

Bottom‐Up Coacervate‐Based Artificial Cells: Integrating Cellular Hallmarks into Complex Life‐Like Systems

Angewandte Chemie, EarlyView.
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo, Angshuman Das, Madelief A. M. Verwiel, Jan C. M. van Hest   +3 more
wiley   +2 more sources

Transcriptional and post-translational regulation of aquaporins in plants. [PDF]

Stress Biol
Yang C, Medison MB, Li Y, Shi Y, Medison RG, Liu H, Wang Y.   +6 more
europepmc   +1 more source

Ribosomal RNA synthesis by RNA polymerase I is subject to premature termination of transcription. [PDF]

Elife
Azouzi C, Schwank K, Queille S, Kwapisz M, Aguirrebengoa M, Henras A, Lebaron S, Tschochner H, Lesne A, Beckouët F, Gadal O, Dez C.   +11 more
europepmc   +1 more source

Genome-wide dynamic nascent transcript profiles reveal that most paused RNA polymerases terminate. [PDF]

Nucleic Acids Res
Mukherjee R, Guertin MJ.
europepmc   +1 more source

Special Issue "Transcriptional Regulation in Plant Development: 2nd Edition". [PDF]

Int J Mol Sci
Vlachonasios KE.
europepmc   +1 more source

Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review). [PDF]

Mol Med Rep
Lee B, Son C, Eom S, Li Y, Kim SH, Park J.   +5 more
europepmc   +1 more source