Results 151 to 160 of about 125,147 (241)

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li   +8 more
wiley   +1 more source

Transcriptional memory dampens heat shock responses in yeast: functional role of Mip6 and its interaction with Rpd3. [PDF]

open access: yesG3 (Bethesda)
Serrano-Quílez J   +3 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Heritable maintenance of chromatin modifications confers transcriptional memory of interferon-γ signaling. [PDF]

open access: yesNat Struct Mol Biol
Mikulski P   +7 more
europepmc   +1 more source

Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. [PDF]

open access: yesCell, 2021
Nuñez JK   +19 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Experience-mediated transcriptional memory correlates with hypoxia resistance in the nervous system of the sea hare <i>Aplysia californica</i>. [PDF]

open access: yesAm J Physiol Regul Integr Comp Physiol
Rodriguez-Casariego JA   +4 more
europepmc   +1 more source

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