Results 51 to 60 of about 4,769,934 (397)
Noise processing by microRNA-mediated circuits: The Incoherent Feed-Forward Loop, revisited [PDF]
, 2016 The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably protein levels. The discovery of small non-coding RNAs (miRNAs) in specific
De Martino, Andrea +3 more
core +2 more sources
Probing the limits to microRNA-mediated control of gene expression [PDF]
, 2016 According to the `ceRNA hypothesis', microRNAs (miRNAs) may act as mediators of an effective positive interaction between long coding or non-coding RNA molecules, carrying significant potential implications for a variety of biological processes.
De Martino, Andrea +3 more
core +10 more sources
TRANSFAC®: transcriptional regulation, from patterns to profiles
Nucleic Acids Res., 2003 The TRANSFAC 1 database on eukaryotic transcriptional regulation, comprising data on transcription factors, their target genes and regulatory binding sites, has been extended and further developed, both in number of entries and in the scope and structure
V. Matys +20 more
semanticscholar +1 more source
Essential Roles of SATB1 in Specifying T Lymphocyte Subsets
Cell Reports, 2017 T cell receptor (TCR) signaling by MHC class I and II induces thymocytes to acquire cytotoxic and helper fates via the induction of Runx3 and ThPOK transcription factors, respectively.
Kiyokazu Kakugawa +12 more
doaj +1 more source
Cells, 2020 PRDI-BF1 (positive regulatory domain I-binding factor 1) and RIZ1 (retinoblastoma protein-interacting zinc finger gene 1) (PR) homologous domain containing (PRDM) transcription factors are expressed in neuronal and stem cell systems, and they exert ...
Paweł Leszczyński +5 more
doaj +1 more source
Circadian rhythms and post-transcriptional regulation in higher plants [PDF]
, 2015 The circadian clock of plants allows them to cope with daily changes in their environment. This is accomplished by the rhythmic regulation of gene expression, in a process that involves many regulatory steps.
Romanowski, Andrés +1 more
core +3 more sources
Transcriptional Regulation of Autophagy: Mechanisms and Diseases
Front. Cell Dev. Biol., 2019 Macro (Autophagy) is a catabolic process that relies on the cooperative function of two organelles: the lysosome and the autophagosome. The recent discovery of a transcriptional gene network that co-regulates the biogenesis and function of these two ...
Chiara Di Malta +2 more
semanticscholar +1 more source
Transcriptional Regulation by P53 [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 Inactivation of p53 is critical for the formation of most tumors. Illumination of the key function(s) of p53 protein in protecting cells from becoming cancerous is therefore a worthy goal. Arguably p53's most important function is to act as a transcription factor that directly regulates perhaps several hundred of the cell's RNA polymerase II (RNAP II ...
Carol Prives, Rachel Beckerman
openaire +3 more sources
Information on Transcriptional Regulation and Signal Transduction of _Escherichia coli_ K-12 Integrated in the Database RegulonDB. [PDF]
, 2010 Since its inception, RegulonDB ("http://regulondb.ccg.unam.mx/":http://regulondb.ccg.unam.mx/) has been a database that compiles information about the regulation of transcription initiation of _Escherichia coli_ K-12. However, we are aware that
Alberto Santos-Zavaleta +7 more
core +5 more sources
Regulation of Transcript Elongation [PDF]
Annual Review of Microbiology, 2015 Bacteria lack subcellular compartments and harbor a single RNA polymerase that synthesizes both structural and protein-coding RNAs, which are cotranscriptionally processed by distinct pathways. Nascent rRNAs fold into elaborate secondary structures and associate with ribosomal proteins, whereas nascent mRNAs are translated by ribosomes.
Irina Artsimovitch, Georgiy A. Belogurov
openaire +3 more sources