Results 291 to 300 of about 345,542 (371)

Unveiling novel susceptibility genes and drug targets for basal cell carcinoma by a cross-tissue transcriptome-wide association study. [PDF]

Discov Oncol
Sun H, Li L, Xin X, Yan J, Huang T.
europepmc   +1 more source

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Subset-based method for cross-tissue transcriptome-wide association studies improves power and interpretability

Xinyu Guo, Nilanjan Chatterjee, Diptavo Dutta   +2 more
openalex   +1 more source

Endothelial Vasoactive Pathways and Renal Outcomes: A Drug-Target Mendelian Randomization and Transcriptome-Wide Association Study. [PDF]

Kidney Dis (Basel)
Ma Y, Xu L, Lin Y, Zhu J, Liu J, Wang L, Chen L.   +6 more
europepmc   +1 more source

Ratoon Season Rice Reduces Methane Emissions by Limiting Acetic Acid Transport to the Rhizosphere and Inhibiting Methanogens

Advanced Science, EarlyView.
This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou, Hailong Xu, Bin Qin, Chaojie Lan, Jinying Li, Bianhong Zhang, Huabin Zhang, Chunlin Guo, Hongfei Chen, Zhongming Fang, Quanzhi Zhao, Wenfei Wang, Changxun Fang, Zhixing Zhang, Wenxiong Lin   +14 more
wiley   +1 more source

Additional file 9: Table S7. of Deciphering the genetic regulation of peripheral blood transcriptome in pigs through expression genome-wide association study and allele-specific expression analysis

, 2017
Tatiana Maroilley, Gaëtan Lemonnier, Jérôme Lecardonnel, D. EsquerrĂŠ, Yuliaxis Ramayo‐Caldas, Marie-José Mercat, Claire Rogel Gaillard, J. EstellĂŠ   +7 more
openalex   +1 more source

scPrediXcan integrates deep learning methods and single-cell data into a cell-type-specific transcriptome-wide association study framework. [PDF]

Cell Genom
Zhou Y, Adeluwa T, Zhu L, Salazar-Magaña S, Sumner S, Kim H, Gona S, Nyasimi F, Kulkarni R, Powell JE, Madduri R, Liu B, Chen M, Im HK.   +13 more
europepmc   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Cell-type aware transcriptome-wide association study of mammographic density phenotypes

Sistig A, Rothstein JH, Zhu S, Head ST, Chang Y, Achacoso N, Alexeeff SE, Arasu V, Gadgil T, Gerstley LD, Margolies LR, Sakoda LC, Shen L, Smith Gueye CL, Villaseñor M, Westley M, MODE/BCAC Consortia, Bhattacharya A, Klein RJ, Habel LA, Song X, Wang P, Sieh W.   +22 more
europepmc   +1 more source

A cross-tissue transcriptome-wide association study reveals GRK4 as a novel susceptibility gene for COPD. [PDF]

Sci Rep
Chen G, Jin Y, Chu C, Zheng Y, Yang C, Chen Y, Zhu X.   +6 more
europepmc   +1 more source