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Evolution: The Plastic Transcriptome [PDF]

open access: yesCurrent Biology, 2006
Studies across a wide range of species point to a surprising degree of plasticity in the transcriptional states that organisms can adopt, suggesting that organisms often respond to environmental challenges through wholesale reprogramming of their gene expression.
openaire   +4 more sources

Genomes and Transcriptomes of Duckweeds [PDF]

open access: yesFrontiers in Chemistry, 2018
Duckweeds (Lemnaceae family) are the smallest flowering plants that adapt to the aquatic environment. They are regarded as the promising sustainable feedstock with the characteristics of high starch storage, fast propagation, and global distribution.
Wenqin Wang   +4 more
openaire   +4 more sources

Dr.seq2: A quality control and analysis pipeline for parallel single cell transcriptome and epigenome data. [PDF]

open access: yesPLoS ONE, 2017
An increasing number of single cell transcriptome and epigenome technologies, including single cell ATAC-seq (scATAC-seq), have been recently developed as powerful tools to analyze the features of many individual cells simultaneously.
Chengchen Zhao   +3 more
doaj   +1 more source

Sequencing and analysis of the gastrula transcriptome of the brittle star Ophiocoma wendtii [PDF]

open access: yes, 2012
Background The gastrula stage represents the point in development at which the three primary germ layers diverge. At this point the gene regulatory networks that specify the germ layers are established and the genes that define the differentiated states ...
Garey, James R.   +4 more
core   +2 more sources

High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell

open access: yesNature Biotechnology, 2019
Single-cell RNA sequencing can reveal the transcriptional state of cells, yet provides little insight into the upstream regulatory landscape associated with open or accessible chromatin regions.
S. Chen, B. Lake, Kun Zhang
semanticscholar   +1 more source

The human olfactory transcriptome [PDF]

open access: yesBMC Genomics, 2016
Olfaction is a versatile sensory mechanism for detecting thousands of volatile odorants. Although molecular basis of odorant signaling is relatively well understood considerable gaps remain in the complete charting of all relevant gene products. To address this challenge, we applied RNAseq to four well-characterized human olfactory epithelial samples ...
Jayant M. Pinto   +10 more
openaire   +3 more sources

High-Frequency Promoter Firing Links THO Complex Function to Heavy Chromatin Formation

open access: yesCell Reports, 2013
The THO complex is involved in transcription, genome stability, and messenger ribonucleoprotein (mRNP) formation, but its precise molecular function remains enigmatic.
John Mouaikel   +8 more
doaj   +1 more source

Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism. [PDF]

open access: yes, 2015
Iberian ham production includes both purebred (IB) and Duroc-crossbred (IBxDU) Iberian pigs, which show important differences in meat quality and production traits, such as muscle growth and fatness.
Ayuso, Miriam   +12 more
core   +4 more sources

Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance The spatial organization of RNAs within cells and spatial patterning of cells within tissues play crucial roles in many biological processes.
C. Xia   +4 more
semanticscholar   +1 more source

Gene Expression Profile Related to the Progression of Preneoplastic Nodules toward Hepatocellular Carcinoma in Rats

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
In this study, we investigated the time course gene expression profile of preneoplastic nodules and hepatocellular carcinomas (HCC) to define the genes implicated in cancer progression in a resistant hepatocyte model. Tissues that included early nodules (
Julio Isael Pérez-Carréon   +9 more
doaj   +1 more source

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