Results 41 to 50 of about 963,153 (378)
Analysis of wheat SAGE tags reveals evidence for widespread antisense transcription [PDF]
, 2008 BACKGROUND: Serial Analysis of Gene Expression (SAGE) is a powerful tool for genome-wide transcription studies. Unlike microarrays, it has the ability to detect novel forms of RNA such as alternatively spliced and antisense transcripts, without the need ...
Barker, Gary L A +8 more
core +2 more sources
And Now, Transcriptomics [PDF]
Neuron, 2002 In this issue of Neuron, report different patterns of 5-HT2C pre-mRNA editing in suicide victims, as compared to controls. Treatment of mice with fluoxetine alters the pattern of 5-HT2C transcript editing in the direction opposite that observed for suicide victims.
openaire +3 more sources
Defining the nociceptor transcriptome [PDF]
Frontiers in Molecular Neuroscience, 2014 Unbiased "omics" techniques, such as next generation RNA-sequencing, can provide entirely novel insights into biological systems. However, cellular heterogeneity presents a significant barrier to analysis and interpretation of these datasets.
Thakur, Matthew +9 more
openaire +5 more sources
BAT: Bisulfite Analysis Toolkit [version 1; referees: 2 approved]
F1000Research, 2017 Here, we present BAT, a modular bisulfite analysis toolkit, that facilitates the analysis of bisulfite sequencing data. It covers the essential analysis steps of read alignment, quality control, extraction of methylation information, and calling of ...
Helene Kretzmer +2 more
doaj +1 more source
RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. [PDF]
, 2011 Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete.
DeRisi, Joseph L +2 more
core +3 more sources
The transcriptome of metamorphosing flatfish [PDF]
BMC Genomics, 2016 Flatfish metamorphosis denotes the extraordinary transformation of a symmetric pelagic larva into an asymmetric benthic juvenile. Metamorphosis in vertebrates is driven by thyroid hormones (THs), but how they orchestrate the cellular, morphological and functional modifications associated with maturation to juvenile/adult states in flatfish is an enigma.
Melody S. Clark +10 more
openaire +5 more sources
Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism. [PDF]
, 2015 Iberian ham production includes both purebred (IB) and Duroc-crossbred (IBxDU) Iberian pigs, which show important differences in meat quality and production traits, such as muscle growth and fatness.
Ayuso, Miriam +12 more
core +4 more sources
Transcriptome assembly from long-read RNA-seq alignments with StringTie2
Genome Biology, 2019 RNA sequencing using the latest single-molecule sequencing instruments produces reads that are thousands of nucleotides long. The ability to assemble these long reads can greatly improve the sensitivity of long-read analyses.
S. Kovaka +5 more
semanticscholar +1 more source
Nature Genetics, 2022 Microglia have emerged as important players in brain aging and pathology. To understand how genetic risk for neurological and psychiatric disorders is related to microglial function, large transcriptome studies are essential.
Katia de Paiva Lopes +19 more
semanticscholar +1 more source
The Escherichia coli transcriptome mostly consists of independently regulated modules [PDF]
, 2019 Underlying cellular responses is a transcriptional regulatory network (TRN) that modulates gene expression. A useful description of the TRN would decompose the transcriptome into targeted effects of individual transcriptional regulators.
A Anand +77 more
core +3 more sources