Results 81 to 90 of about 928,042 (281)

Decryption of sequence, structure, and functional features of SINE repeat elements in SINEUP non-coding RNA-mediated post-transcriptional gene regulation

open access: yesNature Communications
RNA structure folding largely influences RNA regulation by providing flexibility and functional diversity. In silico and in vitro analyses are limited in their ability to capture the intricate relationships between dynamic RNA structure and RNA ...
Harshita Sharma   +6 more
doaj   +1 more source

Imputed genomes of historical horses provide insights into modern breeding

open access: yesiScience, 2023
Summary: Historical genomes can provide important insights into recent genomic changes in horses, especially the development of modern breeds. In this study, we characterized 8.7 million genomic variants from a panel of 430 horses from 73 breeds ...
Evelyn T. Todd   +12 more
doaj  

Transcriptomic profiles in peripheral blood between women with unexplained recurrent implantation failure and recurrent miscarriage and the correlation with endometrium: A pilot study. [PDF]

open access: yesPLoS ONE, 2017
To study the transcriptome profiles in the blood of recurrent implantation failure (RIF), recurrent miscarriage (RM) and fertile women during the window of implantation, and further analysis the correlation of transcriptome profiles between blood and ...
Jin Huang   +8 more
doaj   +1 more source

FreePSI: an alignment-free approach to estimating exon-inclusion ratios without a reference transcriptome. [PDF]

open access: yes, 2017
Alternative splicing plays an important role in many cellular processes of eukaryotic organisms. The exon-inclusion ratio, also known as percent spliced in, is often regarded as one of the most effective measures of alternative splicing events.
Jiang, Tao   +4 more
core   +1 more source

Fungal Transcriptomics

open access: yes, 2018
Transcriptomics, the study of RNA molecules, provides in-depth understanding of cellular functions and the genomic landscape of transcription. Transcriptomics refers to the study of all classes on RNA molecules including mRNA, tRNA, and siRNA. In this chapter, we specifically focus on mRNA, which encodes the protein-coding portion of the genomic DNA ...
Singan, Vasanth R   +2 more
openaire   +4 more sources

At the dawn of the transcriptomic medicine [PDF]

open access: yesExperimental Biology and Medicine, 2020
Progress in genomic analytical technologies has improved our possibilities to obtain information regarding DNA, RNA, and their dynamic changes that occur over time or in response to specific challenges. This information describes the blueprint for cells, tissues, and organisms and has fundamental importance for all living organisms.
Gea Koks   +4 more
openaire   +4 more sources

Small RNA Deep-Sequencing Analyses Reveal a New Regulator of Virulence in Agrobacterium fabrum C58

open access: yesMolecular Plant-Microbe Interactions, 2015
Novel ways of regulating Ti plasmid functions were investigated by studying small RNAs (sRNAs) that are known to act as posttranscriptional regulators in plant pathogenic bacteria.
M. Dequivre   +8 more
doaj   +1 more source

Discovery of a large set of SNP and SSR genetic markers by high-throughput sequencing of pepper (Capsicum annuum) [PDF]

open access: yes, 2012
Genetic markers based on single nucleotide polymorphisms (SNPs) are in increasing demand for genome mapping and fingerprinting of breeding populations in crop plants.
Bouchet, JP   +4 more
core   +3 more sources

rnaSPAdes: a de novo transcriptome assembler and its application to RNA-Seq data

open access: yesbioRxiv, 2018
Summary Possibility to generate large RNA-seq datasets has led to development of various reference-based and de novo transcriptome assemblers with their own strengths and limitations.
Elena Bushmanova   +3 more
semanticscholar   +1 more source

Single-cell transcriptome and translatome dual-omics reveals potential mechanisms of human oocyte maturation

open access: yesNature Communications, 2022
The combined use of transcriptome and translatome as indicators of gene expression profiles is usually more accurate than the use of transcriptomes alone, especially in cell types governed by translational regulation, such as mammalian oocytes.
Wenqi Hu   +24 more
semanticscholar   +1 more source

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