Results 61 to 70 of about 22,603,228 (311)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Transcriptome-wide comparisons.

, 2017
Comparisons of transcriptome-scale SNV profiles for every cell line investigated, with a colour gradient for increasing concordance. The average concordance of non-related cell lines is 67.9%.
Susan Kennedy (424972), Walter Kolch (116087), Pär Lundin (3743371), Erik Fasterius (3743380), Nora Rauch (3743374), Cristina Al-Khalili Szigyarto (3743377), Cinzia Raso (365363), Mathias Uhlén (2427553)   +7 more
core   +1 more source

Transcriptome Analysis Elucidates the Potential Key Genes Involved in Rib Development in bmp6-Deficient Silver Carp (Hypophthalmichthys molitrix)

Animals
Bone morphogenetic protein 6 (BMP-6) is a constituent of the TGF-β superfamily, known for its ability to stimulate bone and cartilage formation. The investigation of bmp6’s involvement in the formation of intermuscular bones in fish has garnered ...
Xiaohui Li, Chunyan Zhang, Cui Feng, Zewen Zhang, Nannan Feng, Hang Sha, Xiangzhong Luo, Guiwei Zou, Hongwei Liang   +8 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

New Insight into the Related Candidate Genes and Molecular Regulatory Mechanisms of Waterlogging Tolerance in Tree Peony Paeonia ostii

Plants
Research on the waterlogging tolerance mechanisms of Paeonia ostii helps us to further understand these mechanisms in the root system and enhance its root bark and oil yields in southern China.
Minghui Zhou, Xiang Liu, Jiayan Zhao, Feng Jiang, Weitao Li, Xu Yan, Yonghong Hu, Junhui Yuan   +7 more
doaj   +1 more source

An Analysis of the Arabidopsis Pollen Transcriptome [PDF]

Plant Physiology, 2007
In flowering plants, male gametogenesis occurs in the anthers. The division of a diploid sporogenic cell results in two cells with very different fates—the tapetal initial cell and the pollen mother cell.
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Global expression analysis of the brown alga Ectocarpus siliculosus (Phaeophyceae) reveals large-scale reprogramming of the transcriptome in response to abiotic stress [PDF]

, 2009
Dittami SM, Scornet D, Petit J-L, et al. Global expression analysis of the brown alga Ectocarpus siliculosus (Phaeophyceae) reveals large-scale reprogramming of the transcriptome in response to abiotic stress. Genome Biology.
Boyen, C., Rainer König, Da Silva, Corinne, König, Rainer, Tonon, Thierry, Van de Peer, Y., Ségurens, Béatrice, Thierry Tonon, Dittami, Simon M, Corre, Erwan, Boyen, Catherine, Strerck, Lieven, Simon M Dittami, Dondrup, M., Corinne Da Silva, Glatting, K.-H., Cock, J.M., Dittami, Simon, Da Silva, C., Lieven, Sterck, Corre, E., Cock, J. Marc, Tonon, T., Glatting, Karl-Heinz, Cock, J Mark, Sterck, L., Béatrice Ségurens, J Mark Cock, Van de Peer, Yves, Lieven Sterck, Cock, J. Mark, Dittami, Simon M., Rouzé, Pierre, Erwan Corre, Sterck, Lieven, Dondrup, Michael, Catherine Boyen, Petit, Jean-Louis, Delphine Scornet, Scornet, Delphine, Dittami, S.M., Segurens, B., Rouzé, P., Jean-Louis Petit, Karl-Heinz Glatting, Michael Dondrup, Pierre Rouzé, Scornet, D., König, R., Petit, J.-L., Yves Van de Peer   +50 more
core   +1 more source

Molecular Regulation of Photosynthetic Carbon Assimilation in Oat Leaves Under Drought Stress

Plants
Common oat (Avena sativa L.) is one of the important minor grain crops in China, and drought stress severely affects its yield and quality. To investigate the drought resistance characteristics of oat seedlings, this study used Baiyan 2, an oat cultivar ...
Yiqun Xu, Liling Jiang, Jia Gao, Wei Zhang, Meijun Zhang, Changlai Liu, Juqing Jia   +6 more
doaj   +1 more source

Response of Downy Oak (Quercus pubescens Willd.) to Climate Change: Transcriptome Assembly, Differential Gene Analysis and Targeted Metabolomics

Plants, 2020
Global change scenarios in the Mediterranean basin predict a precipitation reduction within the coming hundred years. Therefore, increased drought will affect forests both in terms of adaptive ecology and ecosystemic services.
Jean-Philippe Mevy, Beatrice Loriod, Xi Liu, Erwan Corre, Magali Torres, Michael Büttner, Anne Haguenauer, Ilja Marco Reiter, Catherine Fernandez, Thierry Gauquelin   +9 more
doaj   +1 more source