Results 71 to 80 of about 22,603,228 (311)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

transcriptome-­based gene models (LmTGM)

, 2016
Transcriptome-­based gene models for Lissotriton ...
Babik, Wieslaw, Michał Stuglik (3242328), Stuglik, Michał, Wieslaw Babik (648236)   +3 more
core   +1 more source

Deciphering the role of SMU.1147 in peptide-mediated signaling and competence in Streptococcus mutans

Microbiology Spectrum
Streptococcus mutans is a primary cariogenic pathogen involved in dental biofilm formation, a major virulence factor in the development of dental caries. In S.
Jeong Nam Kim, Si-Uk Ryoo, Yeuna Nam
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Regional regulation of transcription in the chicken genome [PDF]

, 2010
Background Over the past years, the relationship between gene transcription and chromosomal location has been studied in a number of different vertebrate genomes. Regional differences in gene expression have been found in several different species.
Bastiaansen John WM, Nie, H., Nie Haisheng, Crooijmans, R.P.M.A., Groenen, M.A.M., Groenen Martien AM, Bastiaansen, J.W.M., Crooijmans Richard PMA, Megens, H.J.W.C., Megens Hendrik-Jan   +9 more
core   +1 more source

Evaluation of Sapindus mukorossi Gaertn Flower Water Extract on In Vitro Anti-Acne Activity

Current Issues in Molecular Biology
Background: Sapindus mukorossi Gaertn is a deciduous tree with saponins as the main active ingredients and has been utilized in medicine and cosmetic industries. Currently, the investigations of S.
Zibing Zhao, Aohuan Zhang, Liya Song, Congfen He, Huaming He   +4 more
doaj   +1 more source

Ultrastructure change and transcriptome analysis of GA3 treatment on seed germination of moso bamboo(Phyllostachys edulis)

Plant Signaling & Behavior, 2022
Exploring the mechanism of Gibberellic acid (GA3) treatment on seed germination of moso bamboo can lay a foundation for its future breeding and research.
Juan Li, Yucong Bai, Yali Xie, Jian Gao
doaj   +1 more source

Transcriptome-wide Analysis of Exosome Targets [PDF]

Molecular Cell, 2012
The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. Here we apply in vivo RNA crosslinking (CRAC) to the nucleases (Rrp44, Rrp6), two structural subunits (Rrp41, Csl4) and a cofactor (Trf4) of the yeast exosome.
Schneider C, Kudla G, Wlotzka W, Tuck A, Tollervey D   +4 more
openaire   +4 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

NCGAS/de-novo-transcriptome-assembly-pipeline: Generating a DOI

, 2020
National Center for Genome Analysis Support (NCGAS) de novo transcriptome assembly ...
Ganote, Carrie, Sanders, Sheri, Papudeshi, Bhavya   +2 more
core   +1 more source