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The Evolution of Gene Expression and the Transcriptome–Phenotype Relationship [PDF]

open access: yesSeminars in Cell and Developmental Biology, 2012
Changes in gene expression underlie the adaptive evolution in many complex phenotypes, and the recent increase in the availability of multi-species comparative transcriptome data has made it possible to scan whole transcriptomes for loci that have experienced adaptive changes in expression.
Judith E. Mank   +2 more
exaly   +5 more sources

RNA-Seq as an Effective Tool for Modern Transcriptomics, A Review-based Study

open access: yesJournal of Applied Research in Plant Sciences, 2022
Transcriptome analysis is a useful method for identification and understanding genes. Finding genes that are differentially expressed between conditions is a crucial aspect of transcriptomics.
Mekibib Million, Tileye Feyissa
doaj   +1 more source

Detecting Rhythmic Gene Expression in Single-cell Transcriptomics

open access: yesJournal of Biological Rhythms, 2023
An autonomous, environmentally synchronizable circadian rhythm is a ubiquitous feature of life on Earth. In multicellular organisms, this rhythm is generated by a transcription-translation feedback loop present in nearly every cell that drives daily expression of thousands of genes in a tissue-dependent manner.
Bingxian Xu   +3 more
openaire   +3 more sources

Gene body DNA methylation in seagrasses: inter- and intraspecific differences and interaction with transcriptome plasticity under heat stress

open access: yesScientific Reports, 2021
The role of DNA methylation and its interaction with gene expression and transcriptome plasticity is poorly understood, and current insight comes mainly from studies in very few model plant species. Here, we study gene body DNA methylation (gbM) and gene
Laura Entrambasaguas   +4 more
doaj   +1 more source

Characterization of Pythium Transcriptome and Gene Expression Analysis at Different Stages of Fermentation. [PDF]

open access: yesPLoS ONE, 2013
The Pythium splendens is a potentially useful organism for the synthesis of large amounts of eicosapentaenoic acid. Peak biomass and lipid accumulation do not occur at the same time and growth temperature has an effect on the fatty acid composition ...
Yuanmin Zhu   +8 more
doaj   +1 more source

Comparability of reference-based and reference-free transcriptome analysis approaches at the gene expression level

open access: yesBMC Bioinformatics, 2021
Background Lately, high-throughput RNA sequencing has been extensively used to elucidate the transcriptome landscape and dynamics of cell types of different species. In particular, for most non-model organisms lacking complete reference genomes with high-
Sung-Gwon Lee, Dokyun Na, Chungoo Park
doaj   +1 more source

Transcriptome of sessile serrated adenoma/polyps is associated with MSI‐high colorectal cancer and decreased expression of CDX2

open access: yesCancer Medicine, 2022
The objective of this study was to elucidate the molecular background of sessile serrated adenoma/polyp (SSA/P) endoscopically resected with comprehensive gene expression analysis.
Daisuke Ohki   +12 more
doaj   +1 more source

A comparison of next generation sequencing technologies for transcriptome assembly and utility for RNA-Seq in a non-model bird. [PDF]

open access: yesPLoS ONE, 2014
De novo assembled transcriptomes, in combination with RNA-Seq, are powerful tools to explore gene sequence and expression level in organisms without reference genomes.
Findley R Finseth, Richard G Harrison
doaj   +1 more source

Gene Expression Transcriptomics Primer 2017

open access: yes, 2021
This is to give anyone a high-level rough guide to Gene Expression. It was originally written in 2017 and therefore is out of date, but the high-level ideas are hopefully still valid.
Mosbergen, Rowland   +3 more
openaire   +1 more source

Reference quantitative transcriptome dataset for adult Caenorhabditis elegans

open access: yesData in Brief, 2019
Caenorhabditis elegans is a nematode widely used in biology and genomics as a model organism. We provide an integrated, quantitative reference map for the transcriptome of whole, wild type Bristol N2 strain C. elegans worms.
Allison Piovesan   +5 more
doaj   +1 more source

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