Results 71 to 80 of about 213,758 (264)

Identification of a rare SEPT9 variant in a family with autosomal dominant Charcot-Marie-Tooth disease

BMC Medical Genetics, 2020
Background Charcot-Marie-Tooth disease (CMT) is one of the most commonly inherited neurological disorders. A growing number of genes, involved in glial and neuronal functions, have been associated with different subtypes of CMT leading to improved ...
Gerrit M. Grosse, Christine Bauer, Bruno Kopp, Christoph Schrader, Alma Osmanovic   +4 more
doaj   +1 more source

Transcriptomics-based points of departure for ecotoxicology – an update

, 2022
Presentation to the Advancing the Pace of Chemical Risk Assessment (APCRA) Meeting Nov 2022 Search for CCTE records in EPA’s Science Inventory by typing in the title at this link.
Dan Villeneuve (5430683)
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A rapid and simple clonality assay for bovine leukemia virus-infected cells by amplified fragment length polymorphism (AFLP) analysis

Microbiology Spectrum
Enzootic bovine leukosis (EBL), although eradicated in some European countries, is still the most common neoplastic disease of cattle, caused by the bovine leukemia virus (BLV).
Tomoko Kobayashi, Sakurako Makimoto, Nagaki Ohnuki, Md Belal Hossain, M. Ishrat Jahan, Misaki Matsuo, Kazuhiko Imakawa, Yorifumi Satou   +7 more
doaj   +1 more source

Transcriptomics-based points of departure for ecotoxicology –an update

, 2021
Presentation to Accelerating the pace of chemical risk assessment(APCRA) (Oct 20210)Search for CCTE records in EPA’s Science Inventory by typing in the title at this link.https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&
Dan Villeneuve (5430683)
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Plasma-Derived miRNAs as Fluid Biomarkers to Differentiate Alzheimer’s and Frontotemporal Dementia

Current Issues in Molecular Biology
Alzheimer’s disease (AD) and Frontotemporal Dementia (FTD) are complex neurodegenerative disorders, often sharing overlapping symptoms. Non-coding RNAs may be involved in pathological processes in these conditions, hence the study of miRNAs isolated from
Rosalinda Di Gerlando, Francesca Dragoni, Evelyne Minucchi, Maria Garofalo, Giulia Perini, Alfredo Costa, Antonio Pisani, Carlo Morasso, Matteo Cotta Ramusino, Stella Gagliardi   +9 more
doaj   +1 more source

uap: reproducible and robust HTS data analysis

BMC Bioinformatics, 2019
Background A lack of reproducibility has been repeatedly criticized in computational research. High throughput sequencing (HTS) data analysis is a complex multi-step process.
Christoph Kämpf, Michael Specht, Alexander Scholz, Sven-Holger Puppel, Gero Doose, Kristin Reiche, Jana Schor, Jörg Hackermüller   +7 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Transcriptomics

Transcriptomics has become an integral approach in all areas of plant sciences. Advances in plant transcriptomics and new tools and techniques that are taking the ground to excel in this field are the emerging horizons of life sciences.
Ali, Sadia, Sekmen, Aşkim Hediye, Ali, Hayssam M.   +2 more
core   +1 more source