Results 81 to 90 of about 225,084 (264)
List of protease inhibitors with transcriptomics and protein expression.
, 2022 List of protease inhibitors with transcriptomics and protein expression.
Antonia Vlahou (114470) +3 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Plasma-Derived miRNAs as Fluid Biomarkers to Differentiate Alzheimer’s and Frontotemporal Dementia
Current Issues in Molecular BiologyAlzheimer’s disease (AD) and Frontotemporal Dementia (FTD) are complex neurodegenerative disorders, often sharing overlapping symptoms. Non-coding RNAs may be involved in pathological processes in these conditions, hence the study of miRNAs isolated from
Rosalinda Di Gerlando +9 more
doaj +1 more source
uap: reproducible and robust HTS data analysis
BMC Bioinformatics, 2019 Background A lack of reproducibility has been repeatedly criticized in computational research. High throughput sequencing (HTS) data analysis is a complex multi-step process.
Christoph Kämpf +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Spatial transcriptomics data for 2 patients with kidney fibrosis
, 2023 spatial transcriptomics dataset from 2 patients , with kidney ...
Fatima Mechta-Grigoriou (7448858)
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Transcriptomics is essential but not sufficient to unravel complex plant–pathogen interactions
Key message: A group of genes that were upregulated in a resistant cultivar while downregulated in a susceptible cultivar in a transcriptomics analysis of potato challenged by Spongospora subterranea infection, did not show the same expression pattern at
Balotf, Sadegh +2 more
core +1 more source
Exploring the frontiers of transcriptomics: Methods, applications, and future perspectives [PDF]
Background: By allowing for the thorough characterization of gene expression, transcriptomics—the study of RNA transcripts generated by the genome—has transformed molecular biology and biomedical research.
Alsadun, Jawaher Sadun +12 more
core +1 more source
Reproducibility in Cancer Transcriptomics Research
, 2022 Slide deck of my talk on Reproducibility in Cancer Transcriptomics Research during October Omics Codeathon organised by the African Society for Bioinformatics and Computational ...
Ahmad, Umar, Ahmad Umar
core +1 more source