Results 111 to 120 of about 152,119 (385)

From clinical application to cognitive enhancement: the example of methylphenidate [PDF]

open access: yes, 2016
Methylphenidate (MPD) is a central nervous system (CNS) stimulant, which belongs to the phenethylamine group and is mainly used in the treatment of attention deficit hyperactive disorder (ADHD).
Busardo', FRANCESCO PAOLO   +4 more
core   +1 more source

Biodegradable Implantable Electronics with Wireless Technology for Real‐Time Clinical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
The article explores how bioresorbable implantable electronics merge wireless communication and power delivery with biodegradable materials to enable real‐time clinical applications. It highlights advances in materials, system design, and medical uses across neural, cardiovascular, digestive, immune, and drug‐delivery systems.
Myeongki Cho   +4 more
wiley   +1 more source

Estimation of the Distribution of Random Parameters in Discrete Time Abstract Parabolic Systems with Unbounded Input and Output: Approximation and Convergence [PDF]

open access: yes, 2019
A finite dimensional abstract approximation and convergence theory is developed for estimation of the distribution of random parameters in infinite dimensional discrete time linear systems with dynamics described by regularly dissipative operators and ...
Luczak, Susan E.   +2 more
core   +1 more source

Striatal Dopamine D2 Receptor Occupancy Induced by Daily Application of Blonanserin Transdermal Patches: Phase II Study in Japanese Patients With Schizophrenia [PDF]

open access: gold, 2020
Hironori Nishibe   +6 more
openalex   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

open access: yesAdvanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz   +3 more
wiley   +1 more source

Transdermal delivery of testosterone [PDF]

open access: yes, 2015
Male hypogonadism has been treated with exogenous testosterone since the 1930s. The early transdermal patches of testosterone became available in the 1980s with gel and solution preparations following subsequent decades.
Hadgraft, J, Lane, ME
core   +1 more source

Engineering bacterial outer membrane vesicles as transdermal nanoplatforms for photo-TRAIL–programmed therapy against melanoma

open access: yesScience Advances, 2020
Transdermal photo-TRAIL therapy by transgenic E. coli–derived outer membrane vesicles eradicates melanoma completely. Melanoma is an aggressive cancer with rapid progression, relapse, and metastasis.
Li-hua Peng   +9 more
semanticscholar   +1 more source

Transdermal Administration of Bromocriptine.

open access: yesBiological and Pharmaceutical Bulletin, 2003
Bromocriptine (BRC) has been mainly used for the inhibition of lactation, treatment of menstrual disorders, Parkinson disease, breast tumours, infertility and brain tumours as a dopamine agonist in clinics. But current BRC formulations have some side effects and bioavailability problems because of hepatic first pass effect.
Lortlar, ND   +3 more
openaire   +4 more sources

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