Results 151 to 160 of about 1,412,226 (251)

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Impact of Drug Hydrophilicity on Transdermal Delivery by Nanoemulsions. [PDF]

Pharmaceutics
Esen Yigit Ö, Lamprecht A.
europepmc   +1 more source

Clinical utility of transdermal delivery of oxybutynin gel via a metered-dose pump in the management of overactive bladder

, 2012
Adrian WaggDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaAbstract: Oxybutynin is an efficacious treatment for overactive bladder, but its clinical utility is hampered by relative intolerability due to its side effect profile ...
Wagg A
core  

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Enhanced Transdermal Delivery of rhHAPLN1 by Soluball^® Promotes Pericellular Matrix Stability and Keratinocyte Protection. [PDF]

Pharmaceutics
Lee KH, Kim KM, Han JH, Oh KT, Kim DK.
europepmc   +1 more source

Tannic acid–metal biomaterials for skin repair: Principles, immune microenvironment modulation, and translational perspectives

BMEMat, EarlyView.
Tannic acid–metal materials are emerging as versatile wound biomaterials, but their value depends on more than multifunctionality. This review maps how tannic acid alone, free metal ions, and coordinated TA–metal systems differ in design logic, immune‐microenvironment effects, and translational potential, offering a practical framework for choosing ...
Shahid Mahmood, Nan Li, Dandan Yang, Chunhui Sun, Yu Wang, Dongzhou Wang, Congcong Zhang   +6 more
wiley   +1 more source

Mechanistic Modelling of Transdermal Delivery Dependence on Drug Properties. [PDF]

Pharm Res
Benbrook N, Zhan W.
europepmc   +1 more source

Gutter Rotation Technique for Percutaneous Ipsilateral Retrieval of a Ruptured SAPIEN‐3 Balloon

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Balloon rupture during transcatheter aortic valve replacement (TAVR) with balloon‐expandable valves is a rare but potentially serious complication that may result in incomplete valve expansion, difficult device retrieval, and vascular injury.
Anne Venkata Ganeshkumar, Guru Chaithanya Kumar Chagalakondu, Naveen Kumar Murki, Siva Sankara Kattinti, Sarat Surapaneni, Somaraju Bhupatiraju   +5 more
wiley   +1 more source

Molecular Dynamics Simulation and Characterization of GelMA/HA Composite Microneedles for Potential Growth Hormone Transdermal Delivery. [PDF]

Gels
Gu J, Zhang H, Liu H, Peng B, Qiao Y, Gong P.   +5 more
europepmc   +1 more source

When Subtle Guiding Catheter‐Induced Stent Deformation Leads to Abluminal Guidewire Passage: Successful IVUS Tip‐Detection‐Guided Bailout

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Incomplete stent apposition at the proximal coronary artery may predispose to subtle guiding catheter–induced stent deformation, creating a gap between the stent and the vessel wall that facilitates inadvertent abluminal guidewire passage. We report a case in which balloon dilatation over an unrecognized abluminal guidewire resulted in severe ...
Yuto Abe, Yuya Hirata, Fumimasa Tabata, Tomomi Koizumi   +3 more
wiley   +1 more source