Results 51 to 60 of about 1,640,128 (340)

A Note on the Trandermal Delivery of Clenbuterol [PDF]

open access: yes, 1992
A modified diffusion/compartmental model has been used to simulate the transdermal uptake of clenbuterol from a matrix-type delivery device. The application of a fresh device every 7 days was found to produce a pseudo-steady state drug plasma profile ...
Göpferich, Achim, Lee, Geoffrey
core   +1 more source

Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected

open access: yesScientia Pharmaceutica, 2020
Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs.
Daniélle van Staden   +2 more
doaj   +1 more source

Recent advances and future prospective of topical and transdermal delivery systems

open access: yesFrontiers in Drug Delivery, 2022
Recent advances in topical and transdermal drug delivery systems have enabled targeted delivery of therapeutics to the site of action by enhancing drug permeation across the stratum corneum and increased bioavailability.
Pronalis Tapfumaneyi   +3 more
semanticscholar   +1 more source

Drug crystallization – implications for topical and transdermal delivery [PDF]

open access: yes, 2016
INTRODUCTION: Crystallization of actives in skin following topical application was suggested by studies in the 1950s and 1960s but is poorly understood.
Hadgraft, J, Lane, ME
core   +1 more source

Transdermal delivery of levosimendan

open access: yesEuropean Journal of Pharmaceutical Sciences, 2000
The aim of this study was to determine if transdermal penetration of levosimendan, a novel positive inotropic drug, could be enhanced and controlled by formulation modifications. Penetration of levosimendan across human epidermis in vitro was determined using abdominal excised skin and diffusion cells.
R, Valjakka-Koskela   +6 more
openaire   +2 more sources

Novel reverse electrodialysis-driven iontophoretic system for topical and transdermal delivery of poorly permeable therapeutic agents

open access: yesDrug Delivery, 2017
Topical and transdermal drug delivery has great potential in non-invasive and non-oral administration of poorly bioavailable therapeutic agents. However, due to the barrier function of the stratum corneum, the drugs that can be clinically feasible ...
Ki-Taek Kim   +10 more
doaj   +1 more source

Delivery of Insulin via Skin Route for the Management of Diabetes Mellitus: Approaches for Breaching the Obstacles

open access: yesPharmaceutics, 2021
Insulin is used for the treatment of diabetes mellitus, which is characterized by hyperglycemia. Subcutaneous injections are the standard mode of delivery for insulin therapy; however, this procedure is very often invasive, which hinders patient ...
Abdul Ahad   +4 more
doaj   +1 more source

Optimizing outcomes in ADHD treatment: From clinical targets to novel delivery systems [PDF]

open access: yes, 2016
Our knowledge and understanding of the underlying neurobiology and symptomatic expression of ADHD has advanced dramatically over the past decade. Associated with these advances has been a similar explosion of new treatment options to individualize ...
Anderson, Richard H   +1 more
core   +2 more sources

Elastic and Ultradeformable Liposomes for Transdermal Delivery of Active Pharmaceutical Ingredients (APIs)

open access: yesInternational Journal of Molecular Sciences, 2021
Administration of active pharmaceutical ingredients (APIs) through the skin, by means of topical drug delivery systems, is an advanced therapeutic approach.
E. Souto   +5 more
semanticscholar   +1 more source

Novel chemical permeation enhancers for transdermal drug delivery

open access: yesAsian Journal of Pharmaceutical Sciences, 2014
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, decreased side effect, easy use and better patient compliance.
Yang Chen   +4 more
doaj   +1 more source

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