Results 51 to 60 of about 1,640,128 (340)
A Note on the Trandermal Delivery of Clenbuterol [PDF]
A modified diffusion/compartmental model has been used to simulate the transdermal uptake of clenbuterol from a matrix-type delivery device. The application of a fresh device every 7 days was found to produce a pseudo-steady state drug plasma profile ...
Göpferich, Achim, Lee, Geoffrey
core +1 more source
Development of Topical/Transdermal Self-Emulsifying Drug Delivery Systems, Not as Simple as Expected
Self-emulsifying drug delivery systems (SEDDSs) originated as an oral lipid-based drug delivery system with the sole purpose of improving delivery of highly lipophilic drugs.
Daniélle van Staden +2 more
doaj +1 more source
Recent advances and future prospective of topical and transdermal delivery systems
Recent advances in topical and transdermal drug delivery systems have enabled targeted delivery of therapeutics to the site of action by enhancing drug permeation across the stratum corneum and increased bioavailability.
Pronalis Tapfumaneyi +3 more
semanticscholar +1 more source
Drug crystallization – implications for topical and transdermal delivery [PDF]
INTRODUCTION: Crystallization of actives in skin following topical application was suggested by studies in the 1950s and 1960s but is poorly understood.
Hadgraft, J, Lane, ME
core +1 more source
Transdermal delivery of levosimendan
The aim of this study was to determine if transdermal penetration of levosimendan, a novel positive inotropic drug, could be enhanced and controlled by formulation modifications. Penetration of levosimendan across human epidermis in vitro was determined using abdominal excised skin and diffusion cells.
R, Valjakka-Koskela +6 more
openaire +2 more sources
Topical and transdermal drug delivery has great potential in non-invasive and non-oral administration of poorly bioavailable therapeutic agents. However, due to the barrier function of the stratum corneum, the drugs that can be clinically feasible ...
Ki-Taek Kim +10 more
doaj +1 more source
Insulin is used for the treatment of diabetes mellitus, which is characterized by hyperglycemia. Subcutaneous injections are the standard mode of delivery for insulin therapy; however, this procedure is very often invasive, which hinders patient ...
Abdul Ahad +4 more
doaj +1 more source
Optimizing outcomes in ADHD treatment: From clinical targets to novel delivery systems [PDF]
Our knowledge and understanding of the underlying neurobiology and symptomatic expression of ADHD has advanced dramatically over the past decade. Associated with these advances has been a similar explosion of new treatment options to individualize ...
Anderson, Richard H +1 more
core +2 more sources
Administration of active pharmaceutical ingredients (APIs) through the skin, by means of topical drug delivery systems, is an advanced therapeutic approach.
E. Souto +5 more
semanticscholar +1 more source
Novel chemical permeation enhancers for transdermal drug delivery
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, decreased side effect, easy use and better patient compliance.
Yang Chen +4 more
doaj +1 more source

