Results 61 to 70 of about 1,412,226 (251)

Elastic liposomes mediated transdermal delivery of verapamil hydrochloride [PDF]

open access: yes, 2018
The aim of present investigation was to formulate and characterize elastic liposomes as a delivery system for transdermal delivery of Verapamil hydrochloride, a drug having low oral bioavailability (approx 20%), short biological half-life and extensive ...
Argal, Ameeta   +2 more
core   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

open access: yesAdvanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi   +3 more
wiley   +1 more source

Optimizing glycerosome formulations via an orthogonal experimental design to enhance transdermal triptolide delivery

open access: yesActa Pharmaceutica, 2022
Triptolide exerts strong anti-inflammatory and immunomodulatory effects; however, its oral administration might be associated with side effects. Transdermal administration can improve the safety of triptolide. In this study, glycerosomes were prepared as
Zhu Chunyun   +5 more
doaj   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang   +11 more
wiley   +1 more source

Chitosan-based transdermal drug delivery systems to overcome skin barrier functions [PDF]

open access: yes, 2019
Transdermal drug delivery system has been developed or being developed to vanquish the downsides associated with conventional strategies as it avoids first pass hepatic metabolism, improved patient compliances, easy termination of therapy, possibility of
Nair, Syam S.
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Approaches and applications in transdermal and transpulmonary gene drug delivery

open access: yesFrontiers in Bioengineering and Biotechnology
Gene therapy has emerged as a pivotal component in the treatment of diverse genetic and acquired human diseases. However, effective gene delivery remains a formidable challenge to overcome. The presence of degrading enzymes, acidic pH conditions, and the
Anni Zhang   +11 more
doaj   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

open access: yesAdvanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

MICRONEEDLE TECHNOLOGY FOR TRANSDERMAL DRUG DELIVERY: APPLICATIONS AND COMBINATION WITH OTHER ENHANCING TECHNIQUES [PDF]

open access: yes, 2016
Transdermal delivery system has been extensively employed over the years owing to its advantages over the conventional delivery systems. However, the stratum corneum hinders the penetration of substances through the skin.
SURYAWANSHI, SANIDHYA   +2 more
core   +1 more source

Transdermal Drug Delivery of Tazarotene: Determining Tazarotene’s Potential in Local Transdermal Therapy

open access: yes, 2023
Retinoid-based drugs, while effective, are associated with systemic toxicity. Topical alternatives offer a safer option, and tazarotene, a third-generation synthetic retinoid, holds promise. This study investigates tazarotene’s transdermal delivery
Helena Hamzehpour   +5 more
core   +1 more source

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