Results 21 to 30 of about 20,274 (254)

Sonophoresis Using Ultrasound Contrast Agents: Dependence on Concentration. [PDF]

PLoS ONE, 2016
Sonophoresis can increase skin permeability to various drugs in transdermal drug delivery. Cavitation is recognized as the predominant mechanism of sonophoresis.
Donghee Park, Gillsoo Song, Yongjun Jo, Jongho Won, Taeyoon Son, Ohrum Cha, Jinho Kim, Byungjo Jung, Hyunjin Park, Chul-Woo Kim, Jongbum Seo   +10 more
doaj   +1 more source

IONTOPHORESIS IN TRANSDERMAL DRUG DELIVERY

INTERNATIONAL JOURNAL OF RECENT TRENDS IN ENGINEERING & RESEARCH, 2019
This paper is designed by keeping in mind the efficiency and ease of drug delivery through transdermal method. Iontophoresis is a technique that is used to deliver the drug through the skin by the flow of electric current. To deliver the correct dosage, current flow through the skin must be actively controlled by automated system.
Reshma Valli Kannan, L. Maceal Tony
openaire   +1 more source

Dissolving microneedle patch-assisted transdermal delivery of methotrexate improve the therapeutic efficacy of rheumatoid arthritis

Drug Delivery, 2023
Methotrexate (MTX) is a first-line treatment for rheumatoid arthritis (RA), but its clinical use is greatly limited by the adverse effects and poor patient compliance caused by traditional oral administration or injection.
Weiman Zhao, Lijie Zheng, Jianhui Yang, Zihui Ma, Xinyi Tao, Qingqing Wang   +5 more
doaj   +1 more source

The Use of Sonophoresis in the Administration of Drugs Throughout the Skin

Journal of Pharmacy & Pharmaceutical Sciences, 2009
Transdermal drug delivery offers an attractive alternative to the conventional drug delivery methods of oral administration and injection. However, the stratum corneum acts as a barrier that limits the penetration of substances through the skin ...
Jose Juan Escobar-Chavez, Dalia Bonilla-Martínez, Martha Angélica Villegas-González, Isabel Marlen Rodríguez-Cruz, Clara Luisa Domínguez-Delgado   +4 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Supersonic Cryogenic Jet Delivery of Polynucleotides Compared With Manual Intradermal Injection

Plastic and Reconstructive Surgery, Global Open
Background:. This study explores an alternative method of delivering polynucleotides (PNs) using a transdermal drug delivery device instead of traditional injection methods.
Michael Kim, MD, Atchima Suwanchinda, MD, PhD, Jin-Hyun Kim, MD, Inneke Jane Hidajat, MBBS, Soo Yeon Park, MD, Kyu-Ho Yi, MD, PhD   +5 more
doaj   +1 more source

A systematic review of carbohydrate-based microneedles: current status and future prospects

Journal of Materials Science: Materials in Medicine, 2021
Highlights The transdermal route can be a promising approach for drug delivery. Microneedles (MNs), a novel and important transdermal drug delivery system (TDDS), are discussed.
Rupali S. Bhadale, Vaishali Y. Londhe
doaj   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

Advanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho, Hyunjae Kim, Seung Eun Yu, Sangmin Lee, Ji Youn Lee, Mi‐Lan Kang, Kang Suk Lee, Young Sik Choi, Hak‐Joon Sung   +8 more
wiley   +1 more source

Heat: A Highly Efficient Skin Enhancer for Transdermal Drug Delivery

Frontiers in Bioengineering and Biotechnology, 2018
Advances in materials science and bionanotechnology have allowed the refinements of current drug delivery systems, expected to facilitate the development of personalized medicine.
Sabine Szunerits, Rabah Boukherroub
doaj   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source