Results 211 to 220 of about 93,495 (232)
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Transdermal Absorption of Radioprotectors Using Permeation-Enhancing Vehicles

Radiation Research, 1990
Radioprotectors are not currently used clinically due to concerns regarding toxicity and uncertainties regarding tumor protection. Topical radioprotection of skin might find clinical applications with protectors such as WR-2721, but laboratory studies in which protectors have been applied in water have not been promising. We have studied the absorption
M, Sodicoff, A, Lamperti, M C, Ziskin
openaire   +2 more sources

Sucrose Esters as Transdermal Permeation Enhancers

2015
Surfactants are widely used excipients in topical formulations, not only for their solubilizing and emulsifying properties but also for their well-known capacity to enhance drug permeation. Although nonionic surfactants are frequently chosen because of their mild effect on the skin, they share a low efficacy as permeation enhancers.
María Guadalupe Nava-Arzaluz   +2 more
openaire   +1 more source

Transdermal delivery of naloxone: ex vivo permeation studies

International Journal of Pharmaceutics, 1999
The purpose of this investigation was to study the feasibility of transdermal drug delivery of the potent opioid antagonist naloxone. The pharmacokinetic profile of naloxone makes it a suitable candidate for transdermal delivery. Ex vivo permeation of naloxone through excised rat skin was studied using a diffusion cell.
J, Jaiswal, R, Poduri, R, Panchagnula
openaire   +2 more sources

Improvement of transdermal permeation of captopril by iontophoresis.

Acta pharmacologica Sinica, 2001
The feasibility of iontophoresis on the transdermal delivery of captopril was studied.Iontophoresis was employed for enhancing transdermal transport of captopril through rat skin in vitro and in vivo.It was demonstrated that the iontophoresis-induced flux of captopril was affected by various factors such as pH, ionic concentration, and the ...
H, Wang, H M, Hou
openaire   +1 more source

In vitro transdermal permeation and penetration properties for transfersomes of brucine

China Journal of Chinese Materia Medica, 2016
To prepare the liposomes and transfersomes of brucine, characterize their pharmaceutical properties, and compare their in vitro transdermal permeation properties. The liposomes and transfersomes of brucine were prepared by ammonium sulfate gradient method to investigate their pharmaceutical properties such as the particle size, encapsulation efficiency
Yu, Wu, Jun, Chen, Yun, Fang, Jie, Dong
openaire   +2 more sources

Transdermal permeation of tetracaine hydrochloride by lecithin microemulsion: In vivo

Colloids and Surfaces B: Biointerfaces, 2006
In vivo transdermal permeation of tetracaine hydrochloride encapsulated in lecithin water-in-oil and oil-in-water microemulsion was studied. The effect of the composition of the lecithin microemulsion on analgesic response of tetracaine hydrochloride was evaluated on Wistar rats by tail flick method.
Mohammad, Changez   +2 more
openaire   +2 more sources

Applications of ultrasonic skin permeation in transdermal drug delivery

Expert Opinion on Drug Delivery, 2008
Transdermal ultrasound-mediated drug delivery has been studied as a method for needle-less, non-invasive drug administration. Potential obstacles include the stratum corneum, which is not sufficiently passively permeable to allow effective transfer of many medications into the bloodstream without active methods.
openaire   +2 more sources

Transdermal Permeation

2012
Nezih Pala   +23 more
openaire   +1 more source

Comparison of Ionic Liquids and Chemical Permeation Enhancers for Transdermal Drug Delivery

Advanced Functional Materials, 2020
Samir Mitragotri   +2 more
exaly  

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