Results 1 to 10 of about 507,984 (249)

Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj [PDF]

open access: yes, 2009
Background: Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors.
Silke Schüle   +61 more
core   +9 more sources

Co-transduction of dual-adeno-associated virus vectors in the neonatal and adult mouse utricles

open access: yesFrontiers in Molecular Neuroscience, 2022
Adeno-associated virus (AAV)-mediated gene transfer is an efficient method of gene over-expression in the vestibular end organs. However, AAV has limited usefulness for delivering a large gene, or multiple genes, due to its small packaging capacity (<
Zhong-Rui Chen   +19 more
doaj   +1 more source

Lost in Transduction: Transductive Transfer Learning in Text Classification [PDF]

open access: yesACM Transactions on Knowledge Discovery from Data, 2021
Obtaining high-quality labelled data for training a classifier in a new application domain is often costly. Transfer Learning (a.k.a. “Inductive Transfer”) tries to alleviate these costs by transferring, to the “target” domain of interest, knowledge available from a different “source” domain.
Moreo, Alejandro   +2 more
openaire   +4 more sources

Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization

open access: yesBiomedicines, 2021
NK cells are the first line of defense against viruses and malignant cells, and their natural functionality makes these cells a promising candidate for cancer cell therapy.
Maria A. Streltsova   +5 more
doaj   +1 more source

Genetic Engineering and Enrichment of Human NK Cells for CAR-Enhanced Immunotherapy of Hematological Malignancies

open access: yesFrontiers in Immunology, 2022
The great clinical success of chimeric antigen receptor (CAR) T cells has unlocked new levels of immunotherapy for hematological malignancies. Genetically modifying natural killer (NK) cells as alternative CAR immune effector cells is also highly ...
Maren Soldierer   +19 more
doaj   +1 more source

Segmentation by transduction [PDF]

open access: yes2008 IEEE Conference on Computer Vision and Pattern Recognition, 2008
This paper addresses the problem of segmenting an image into regions consistent with user-supplied seeds (e.g., a sparse set of broad brush strokes). We view this task as a statistical transductive inference, in which some pixels are already associated with given zones and the remaining ones need to be classified.
Duchenne, Olivier   +4 more
openaire   +2 more sources

Supporting Student Transduction of Meanings Across Modes in Primary School Astronomy

open access: yesFrontiers in Communication, 2022
The multimodal nature of knowledge development and learning in science is now increasingly recognized. While researchers have focused on identifying how different representational modes afford meaning-making, the question of how students are guided to ...
Russell Tytler, Vaughan Prain
doaj   +1 more source

What Do We Hear When We Hear Microbe Sounds

open access: yesPulse, 2022
The concept of the Anthropocene, based on the premise that mankind has become a major geological force in its own right, has grown into a central theme with issues such as ecological crisis, climate change, or sustainable futures.
Emre Sünter
doaj   +1 more source

The Age of Phage: Friend or Foe in the New Dawn of Therapeutic and Biocontrol Applications?

open access: yesPharmaceuticals, 2021
Extended overuse and misuse of antibiotics and other antibacterial agents has resulted in an antimicrobial resistance crisis. Bacteriophages, viruses that infect bacteria, have emerged as a legitimate alternative antibacterial agent with a wide scope of ...
Ahmad Y. Hassan   +3 more
doaj   +1 more source

Comparison of the Transduction Capacity of AAV5 and AAV PHP.eB Serotypes in Hippocampus Astroglia

open access: yesNeuroglia, 2023
In the present study, we compared the astrocyte-transducing potential of the relatively novel engineered AAV PHP.eB serotype and the well-examined conventional AAV5 serotype.
Anastasia Borodinova   +2 more
doaj   +1 more source

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