Results 21 to 30 of about 507,984 (249)

Construction of stable coxsackievirus and adenovirus receptor-expressing 3T3-L1 cells

open access: yesJournal of Lipid Research, 2001
3T3-L1 cells have been used as a model to study the differentiation and physiology of adipocytes. Exogenous expression of proteins in these cells offers the prospect of understanding the protein's function(s) in adipose tissue.
David J. Orlicky   +2 more
doaj   +1 more source

Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway. [PDF]

open access: yes, 2003
A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Davidoff, AM   +4 more
core   +1 more source

Transductive Ordinal Regression [PDF]

open access: yesIEEE Transactions on Neural Networks and Learning Systems, 2012
Ordinal regression is commonly formulated as a multi-class problem with ordinal constraints. The challenge of designing accurate classifiers for ordinal regression generally increases with the number of classes involved, due to the large number of labeled patterns that are needed.
Chun-Wei Seah   +2 more
openaire   +4 more sources

Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant

open access: yesMolecular Therapy: Nucleic Acids, 2014
HIV-1 derived vectors are among the most efficient for gene transduction in mammalian tissues. As the parent virus, they carry out vector genome insertion into the host cell chromatin.
Muhammad Qamar Saeed   +17 more
doaj   +1 more source

Genetic engineering of human and mouse CD4+ and CD8+ Tregs using lentiviral vectors encoding chimeric antigen receptors

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
The last decade has seen a significant increase of cell therapy protocols using effector T cells (Teffs) in particular, but also, more recently, non-engineered and expanded polyclonal regulatory T cells (Tregs) to control pathological immune responses ...
Nadège Vimond   +4 more
doaj   +1 more source

Cognitive Phonetics: The Transduction of Distinctive Features at the Phonology-Phonetics Interface

open access: yesBiolinguistics, 2018
We propose that the interface between phonology and phonetics is mediated by a transduction process that converts elementary units of phonological computation, features, into temporally coordinated neuromuscular patterns, called ‘True Phonetic ...
Veno Volenec, Charles Reiss
doaj   +1 more source

A Short Introduction to Bacteriophages

open access: yesTrends in Peptide and Protein Sciences, 2016
First discovered in the 19th century, bacteriophages (phages) are bacterial viruses and the most widespread entities on earth. Phages have multiple important roles in maintaining the bacterial population, carbon cycling, bacterial pathogenicity, and ...
Ramin Mazaheri Nezhad Fard
doaj   +1 more source

Learning by Transduction

open access: yesCoRR, 2013
Appears in Proceedings of the Fourteenth Conference on Uncertainty in Artificial Intelligence (UAI1998)
Alexander Gammerman   +2 more
openaire   +3 more sources

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]

open access: yes, 2010
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada   +9 more
core   +1 more source

Coherent motion of stereocilia assures the concerted gating of hair-cell transduction channels

open access: yes, 2007
The hair cell's mechanoreceptive organelle, the hair bundle, is highly sensitive because its transduction channels open over a very narrow range of displacements.
A J Hudspeth   +24 more
core   +4 more sources

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