Results 11 to 20 of about 507,984 (249)
Journal of Experimental & Clinical Cancer Research, 2019 Background Despite the increasing progress in targeted and immune based-directed therapies for other solid organ malignancies, currently there is no targeted therapy available for TNBCs.
Murugan Kalimutho +9 more
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Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]
, 2017 The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C +3 more
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Modeling the Electrostatic Actuation of Nanomechanical Pillar Dimers
Frontiers in Mechanical Engineering, 2021 With their unparalleled mass sensitivity, enabling single-molecule mass spectrometry, nanomechanical resonators have the potential to considerably improve existing sensor technology.
Andreas Kainz +3 more
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Molecular Therapy: Methods & Clinical Development, 2017 Ex vivo transduction of human CD34+ hematopoietic stem/progenitor cells (hCD34+ HSPCs) and T lymphocytes is a key process that requires high efficiency and low toxicity to achieve effective clinical results.
Claudia Piovan +10 more
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Viruses, 2023 Adeno-associated virus (AAV) vectors are among the most widely used delivery vehicles for in vivo gene therapy as they mediate robust and sustained transgene expression with limited toxicity.
Darrick L. Yu +7 more
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Tropism and transduction of oncolytic adenovirus vectors in prostate cancer therapy
Frontiers in Bioscience-Landmark, 2021 Oncolytic adenovirus has been applied in cancer therapy because of several advantages such as cost-effective production, high transduction efficiency and low toxicity.
Chuang Wu +6 more
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eLife, 2023 Melanopsin signaling within intrinsically photosensitive retinal ganglion cell (ipRGC) subtypes impacts a broad range of behaviors from circadian photoentrainment to conscious visual perception.
Ely Contreras +4 more
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Modeling, Simulation and Application of Bacterial Transduction in Genetic Algorithms [PDF]
, 2009 At present, all methods in Evolutionary Computation are bioinspired in the fundamental principles of neo-Darwinism as well as on a vertical gene transfer. Thus, on a mechanism in which an organism receives genetic material from its ancestor.
Carlos Perales-Gravan +2 more
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Simondon and Bohm between determinism and indeterminism [PDF]
Filozofija i Društvo, 2022 The radical redefinition of the landscape of physics that followed the contributions of Niels Bohr and Werner Heisenberg at the start of the 20th century led to plethora [of] new perspectives on age-old metaphysical questions on determinism and ...
Jovićević Andrej
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Efficient Transduction and Expansion of Ovine Macrophages for Gene Therapy Implementations
Veterinary Sciences, 2018 A number of bacteria provoking zoonotic diseases present intracellular survival and a host cell tropism limited to the monocyte/macrophage lineage. Thus, infection is rendered difficult to eradicate, causing chronic inflammatory reactions to the host and
Garyfalia Karponi +3 more
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