Results 211 to 220 of about 145,799 (355)

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Gene Therapy of Beta Hemoglobinopathies. [PDF]

Biomedicines
Testa U, Pelosi E, Castelli G.
europepmc   +1 more source

Rho Kinase Inhibitor Y-27632 Prolongs the Life Span of Adult Human Keratinocytes, Enhances Skin Equivalent Development, and Facilitates Lentiviral Transduction

, 2012
Ellen H. van den Bogaard, Diana Rodijk‐Olthuis, Patrick A.M. Jansen, Ivonne M.J.J. van Vlijmen‐Willems, P.E.J. van Erp, Irma Joosten, Patrick L.J.M. Zeeuwen, Joost Schalkwijk   +7 more
openalex   +2 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

519. DNA Delivery Was Enhanced by Novel Protein Transduction Domain, Hph-1

, 2007

openalex   +1 more source

98. Bortezomib Enhances AAV Vector Mediated Transduction But Inhibits the Secretion of Transgene Product [PDF]

, 2015
Yuanqing Lu, Ahmed S. Elshikha, George Marek, Mohammad Ahsanul Akbar, Guohua An, Mark Brantly, Sihong Song   +6 more
openalex   +1 more source

Two‐Dimensional Materials as a Multiproperty Sensing Platform

Advanced Functional Materials, EarlyView.
Various sensing modalities enabled and/or enhanced by two‐dimensional (2D) materials are reviewed. The domains considered for sensing include: 1) optoelectronics, 2) quantum defects, 3) scanning probe microscopy, 4) nanomechanics, and 5) bio‐ and chemosensing.
Dipankar Jana, Shubhrasish Mukherjee, Dmitrii Litvinov, Magdalena Grzeszczyk, Sergey Grebenchuk, Makars Šiškins, Virgil Gavriliuc, Yihang Ouyang, Changyi Chen, Yuxuan Ye, Meng Yiming, Maciej Koperski   +11 more
wiley   +1 more source

Enhancer activation from transposable elements in extrachromosomal DNA. [PDF]

Nat Cell Biol
Kraft K, Murphy SE, Jones MG, Shi Q, Bhargava-Shah A, Luong C, Hung KL, He BJ, Li R, Park SK, Montgomery MT, Weiser NE, Wang Y, Luebeck J, Bafna V, Boeke JD, Mischel PS, Boettiger AN, Chang HY.   +18 more
europepmc   +1 more source

Tunable and Recyclable Piezoelectric Biomaterials via Ion‐Directed Guanine‐Quadruplex Assembly

Advanced Functional Materials, EarlyView.
Guanine‐quadruplex (GQ) assemblies, formed via ion‐mediated self‐assembly of amphiphilic guanine derivatives, are introduced as tunable and recyclable piezoelectric biomaterials. Distinct alkali ions induce unique dipole configurations and piezoelectric outputs, with K⁺ yielding the highest performance.
Seungho Lee, Sangyun Na, Yumi Cho, Gaeun Park, Seung Hak Oh, Jaejun Kim, Byoung‐Ki Cho, Sang Kyu Kwak, Ja‐Hyoung Ryu, Hyunhyub Ko   +9 more
wiley   +1 more source

Enhancer-mediated NR2F2 recruitment activates BGN to promote tumor growth and shape tumor microenvironment in papillary thyroid cancer. [PDF]

Theranostics
Tao M, Ruan X, Yu J, Dong Q, Luo W, Zhang W, Tian M, Hou X, Hu L, Zhao J, Li D, Hao J, Wei S, Zheng X, Gao M.   +14 more
europepmc   +1 more source