Results 21 to 30 of about 154 (98)

A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo. [PDF]

J Cosmet Dermatol
ABSTRACT Background Vitiligo is a chronic skin disorder characterized by loss of melanocytes, causing depigmentation and psychological distress. Its pathogenesis is complex and multifactorial, involving genetic predisposition, autoimmune, oxidative stress, and neurogenic mechanisms.
Sallehuddin N, Fadilah NIM, Fauzi MB, Maarof M.   +3 more
europepmc   +2 more sources

A DoE-based development and characterization of Nadifloxacin-loaded transethosomal gel for the treatment of Acne vulgaris

Future Journal of Pharmaceutical Sciences
Background The objective of this current research was to enhance the topical delivery of Nadifloxacin (NDFX) by incorporating it into a transethosomal gel formulation.
Sujeet Patil, Panchaxari M. Dandagi, Taufik Kazi, Sujay Hulyalkar, Prakash Biradar, Vijay Kumbar   +5 more
doaj   +2 more sources

IMPROVED SKIN PENETRATION AND DEPOSITION OF NAFTIFINE FROM TRANSETHOSOMES AND TRANSETHOSOMAL GEL FORMULATIONS

FARMACIA, 2022
The main objective of the present study was to develop and characterize naftifine loaded transethosomes and their comparison with marketed cream of naftifine (Exoderil (R), Sandoz Turkiye) for enhanced dermal delivery. Transethosomes loaded with naftifine were developed using the film dispersion method and evaluated for particle size and size ...
Guzel, Imren Esenturk, Gungor, Sevgi, Erdal, Meryem Sedef   +2 more
openaire   +2 more sources

Formulation, Development and Evaluation of Ketoprofen Loaded Transethosomes Gel

Journal of Drug Delivery and Therapeutics, 2022
Ketoprofen ([RS]2-[3-benzoylphenyl]-propionic acid) is widely employed as a non-steroidal anti-inflammatory drug (NSAID). Ketoprofen is offered in a variety of forms in the pharmaceutical industry, including coated tablets, capsules, topical gels, transdermal patches, liquid spray, and injection solutions. The purpose of present work was to look at the
Narendra Kumar Joshi, Vivek Gupta
openaire   +2 more sources

Exploring the potential of transethosomes in therapeutic delivery: A comprehensive review

MedComm – Biomaterials and Applications, Volume 2, Issue 4, December 2023., 2023
Transethosomes are drug‐delivery vesicles composed of a continuous phospholipid bilayer membrane containing an ethosomal core. This review explores their potential, addressing limitations of conventional methods. The impact of formulation components, effective targeting, and production techniques are discussed.
Pavani Chowdary, Ananya Padmakumar, Aravind Kumar Rengan   +2 more
wiley   +1 more source

IN VITRO PENETRATION TESTS OF TRANSETHOSOME GEL PREPARATIONS CONTAINING CAPSAICIN

International Journal of Applied Pharmaceutics, 2017
Objective: Capsaicin is an active compound found in chili pepper and has been shown to have analgesic, antioxidant, anticancer, and anti-obesityproperties. To improve its penetration into the skin, capsaicin was prepared in a transethosome vesicle. Importantly, transethosomes are vesicles thatconsist of phosphatidylcholine, surfactant, and ethanol.
Nuraini Azizah, Erny Sagita, Iskandarsyah Iskandarsyah   +2 more
openaire   +2 more sources

Development and evaluation of eugenol-loaded transethosomal gel as a potential topical therapy for onychomycosis: In Vitro dose determination, drug release profiling, and antifungal activity against Trichophyton rubrum

Next Materials
Introduction: Onychomycosis is a serious nail condition primarily caused by Trichophyton rubrum. Eugenol, a natural phenolic compound with antifungal properties, serves as a safer treatment approach for onychomycosis, showing low aqueous solubility and ...
Ishu Garg, Shreya Rawat, Urmi Chaurasia, Tushar Negi, Shivani Rawat, Madhu Verma, Iti Chauhan   +6 more
doaj   +1 more source

Ginger Extract–Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model

International Journal of Nanomedicine, 2023
Abeer S Hassan,1 Amal Hofni,2 Mohammed AS Abourehab,3 Iman AM Abdel-Rahman4 1Department of Pharmaceutics, Faculty of Pharmacy, South Valley University, Qena, Egypt; 2Department of Pharmacology and Toxicology, Faculty of Pharmacy, South Valley University,
Hassan AS, Hofni A, Abourehab MAS, Abdel-Rahman IAM   +3 more
doaj  

Progress in Lipid and Inorganic Nanocarriers for Enhanced Skin Drug Delivery

Advanced NanoBiomed Research, Volume 4, Issue 6, June 2024.
Nanocarriers for topical and transdermal drug delivery consist of two primary types: lipid and inorganic. The most used are lipid nanocarriers, owing to their biocompatibility and ability to encapsulate a wide range of drugs. Despite the large number of nanocarriers being investigated, only a few have been clinically approved.
Lamyaa Albakr, Hongyuan Du, Xiyuan Zhang, Himanshu Kathuria, Ahmed Fahmi Anwar‐Fadzil, Nial J. Wheate, Lifeng Kang   +6 more
wiley   +1 more source

Systematic Development of Transethosomal Gel System of Piroxicam: Formulation Optimization, In Vitro Evaluation, and Ex Vivo Assessment [PDF]

AAPS PharmSciTech, 2016
Piroxicam is used in the treatment of rheumatoid arthritis, osteoarthritis, and other inflammatory diseases. Upon oral administration, it is reported to cause ulcerative colitis, gastrointestinal irritation, edema and peptic ulcer. Hence, an alternative delivery system has been designed in the form of transethosome.
Varun Garg, Harmanpreet Singh, Amit Bhatia, Kaisar Raza, Sachin Kumar Singh, Bhupinder Singh, Sarwar Beg   +6 more
openaire   +2 more sources