Development and Optimization of Erythromycin Loaded Transethosomes Cinnamon Oil Based Emulgel for Antimicrobial Efficiency [PDF]
Gels, 2023 Erythromycin (EM) is a macrolide antibiotic that is frequently used to treat skin bacterial infections. It has a short half-life (1–1.5 h), instability in stomach pH, and a low oral bioavailability.
Marwa H Abdallah +2 more
exaly +4 more sources
Nutlin-3 Loaded Ethosomes and Transethosomes to Prevent UV-Associated Skin Damage [PDF]
LifeThe skin’s protective mechanisms, in some cases, are not able to counteract the destructive effects induced by UV radiations, resulting in dermatological diseases, as well as skin aging.
Elisabetta Esposito +2 more
exaly +4 more sources
Preparation and Characterization of Transethosome Formulation for the Enhanced Delivery of Sinapic Acid [PDF]
Pharmaceutics, 2023 Sinapic acid (SA) is a bioactive phenolic acid; its diverse properties are its anti-inflammatory, antioxidant, anticancer, and antibacterial activities. The bioactive compound SA is poorly soluble in water.
Yousef A. Bin Jardan +3 more
doaj +2 more sources
Novel Transethosomal Gel Containing Miconazole Nitrate; Development, Characterization, and Enhanced Antifungal Activity [PDF]
Pharmaceutics, 2023 Miconazole nitrate (MCNR) is a BCS class II antifungal drug with poor water solubility. Although numerous attempts have been made to increase its solubility, formulation researchers struggle with this significant issue. Transethosomes are promising novel
Zara Asghar +4 more
doaj +2 more sources
Ethosomes and Transethosomes for Mangiferin Transdermal Delivery
Antioxidants, 2021 Mangiferin is a natural glucosyl xanthone with antioxidant and anti-inflammatory activity, making it suitable for protection against cutaneous diseases.
Maddalena Sguizzato +2 more
exaly +3 more sources
Exploring the potential of transethosomes in therapeutic delivery: A comprehensive review
MedComm – Biomaterials and Applications, 2023 The growing need for innovative drug delivery systems has led to extensive research to address the limitations associated with conventional dosage forms.
Ananya Padmakumar, Aravind Kumar Rengan
exaly +2 more sources
Development and Evaluation of Azithromycin-Loaded Transethosomes for Enhanced Dermal Delivery and Antibacterial Efficacy [PDF]
PharmaceuticsBackground/Objectives: The topical delivery of antibiotics through transethosomes shows promise for enhancing its dermal delivery for the treatment of skin infections.
Meriem Rezigue +4 more
doaj +2 more sources
Formulation Development, Optimization by Box–Behnken Design, and In Vitro and Ex Vivo Characterization of Hexatriacontane-Loaded Transethosomal Gel for Antimicrobial Treatment for Skin Infections [PDF]
Gels, 2023 There are many different infections and factors that can lead to skin illnesses, but bacteria and fungi are the most frequent. The goal of this study was to develop a hexatriacontane-loaded transethosome (HTC-TES) for treating skin conditions caused by ...
Alhussain H. Aodah +10 more
doaj +2 more sources
Fabrication and Evaluation of Voriconazole Loaded Transethosomal Gel for Enhanced Antifungal and Antileishmanial Activity [PDF]
Molecules, 2022 Voriconazole (VRC) is a broad-spectrum antifungal agent belonging to BCS class II (biopharmaceutical classification system). Despite many efforts to enhance its solubility, this primary issue still remains challenging for formulation scientists ...
Mudassir Farooq +10 more
doaj +2 more sources
Ultradeformable Vesicles for Wound Healing: Ethosomes, Transferosomes, and Transethosomes in Topical Drug Delivery [PDF]
PharmaceuticsWound healing is a dynamic and multifaceted biological process involving hemostasis, inflammation, proliferation, and tissue remodeling. Topical therapy is widely preferred for wound management due to its localized action and reduced systemic adverse ...
Shery Jacob +2 more
doaj +2 more sources