Results 41 to 50 of about 332 (146)

Metformin HCl-loaded transethosomal gel; development, characterization, and antidiabetic potential evaluation in the diabetes-induced rat model

Drug Delivery, 2023
Herein we designed, optimized, and characterized the Metformin Hydrochloride Transethosomes (MTF-TES) and incorporate them into Chitosan gel to develop Metformin Hydrochloride loaded Transethosomal gel (MTF-TES gel) that provides a sustained release ...
Kainat Nousheen, Fakhar Ud Din, Humzah Jamshaid, Rabia Afza, Saif Ullah Khan, Maimoona Malik, Zakir Ali, Sibgha Batool, Alam Zeb, Abid Mehmood Yousaf, Ali H. Almari, Saud Alqahtani, Salman Khan, Gul Majid Khan   +13 more
doaj   +1 more source

Transethosomes: A Breakthrough System for Transdermal and Topical Drug Delivery

Pakistan BioMedical Journal, 2022
The major hindrance in transdermal delivery of drugs is complex barrier of stratum corneum.     New generations lipid based nano-system, particularly transethosomes have ability to permeate from rigid network of stratum corneum. They have proved to be a promising tool for the transport of drugs.
Jawad Ali, Reesha Raza, Sibgha Ameen, Anam Arshad, Fauzia Karim, Muhammad Waseem Akram, Lubna Shakir   +6 more
openaire   +1 more source

Ginger Extract–Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model

International Journal of Nanomedicine, 2023
Abeer S Hassan,1 Amal Hofni,2 Mohammed AS Abourehab,3 Iman AM Abdel-Rahman4 1Department of Pharmaceutics, Faculty of Pharmacy, South Valley University, Qena, Egypt; 2Department of Pharmacology and Toxicology, Faculty of Pharmacy, South Valley University,
Hassan AS, Hofni A, Abourehab MAS, Abdel-Rahman IAM   +3 more
doaj  

Development of Transethosomes Loaded with Fruit Extract from Carissa carandas L. as a Brightening and Anti-Aging Cosmeceutical Ingredient

Cosmetics
The ethanolic extract of Carissa carandas L. (ECE) inhibited the enzyme tyrosinase, enhanced the proliferation of normal human dermal fibroblast cells, and increased the formation of collagen type I, indicating possible anti-aging and whitening effects ...
Sitthiphong Soradech, Worawan Tiatragoon, Phongsapak Phanphothong, Kanyarat Ouamkan, Pattarawadee Kengkwasingh, Supatjaree Ruengsomwong, Somkamol Intawong, Thanchanok Muangman   +7 more
doaj   +1 more source

Transdermal Delivery of Telmisartan: Formulation, in vitro, ex vivo, Iontophoretic Permeation Enhancement and Comparative Pharmacokinetic Study in Rats

Drug Design, Development and Therapy, 2021
Mahmoud Teaima,1 Rehab Abdelmonem,2 Yomna A Adel,3 Mohamed A El-Nabarawi,1 Tayseer M El-Nawawy3 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; 2Department of Industrial Pharmacy, College of ...
Teaima M, Abdelmonem R, Adel YA, El-Nabarawi MA, El-Nawawy TM   +4 more
doaj  

“Plurethosome” as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation

Pharmaceutics, 2021
Human skin is dramatically exposed to toxic pollutants such as ozone. To counteract the skin disorders induced by the air pollution, natural antioxidants such as mangiferin could be employed.
Maddalena Sguizzato, Francesca Ferrara, Paolo Mariani, Alessia Pepe, Rita Cortesi, Nicolas Huang, Fanny Simelière, Paola Boldrini, Anna Baldisserotto, Giuseppe Valacchi, Elisabetta Esposito   +10 more
doaj   +1 more source

Beneficial Effects Exerted by Paeonol in the Management of Atherosclerosis

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Atherosclerosis, a chronic luminal stenosis disorder occurred in large and medium arteries, is the principle pathological basis of cardiovascular diseases with the highest morbidity and mortality worldwide. In oriental countries, traditional Chinese medicine Cortex Moutan has been widely used for the treatment of atherosclerosis‐related illnesses for ...
Li Lu, Yating Qin, Chen Chen, Xiaomei Guo, Ryuichi Morishita   +4 more
wiley   +1 more source

Nanoarchitectures in Management of Fungal Diseases: An Overview

Applied Sciences, 2021
Fungal infections, from mild itching to fatal infections, lead to chronic diseases and death. Antifungal agents have incorporated chemical compounds and natural products/phytoconstituents in the management of fungal diseases. In contrast to antibacterial
Vijay Mishra, Manvendra Singh, Yachana Mishra, Nitin Charbe, Pallavi Nayak, Kalvatala Sudhakar, Alaa A. A. Aljabali, Seyed H. Shahcheraghi, Hamid Bakshi, Ángel Serrano-Aroca, Murtaza M. Tambuwala   +10 more
doaj   +1 more source

Cutaneous Photoaging: A Review of Melasma and Nanotechnological Approaches to Its Control

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Skin is a complex tissue that performs important functions to protect the body against environmental stressors and also synthesizes melanin, a pigment essential for preventing keratinocyte DNA from UV‐induced damage. Excessive solar radiation triggers skin photoaging, leading to hyperactivation of melanocytes and the development of melasma on the face.
Daniela Mayra de Oliveira Figueiredo, Mateus Freire Leite, Suraiya Saleem   +2 more
wiley   +1 more source

Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Eugenol (Eug), a volatile phenolic bioactive compound with formula of C10H12O2 have been reported with anticancer, antidiabetic, cardio‐ and pulmonary protective role. Moreover, it has the ability to improve gut health and prevent neurodegenerative disorders. According to WHO, the safe dose of Eug is 2.5 mg/kg for consumption.
Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Aimen Mazhar, Waqas Ahmad Khan, Muhammad Imran, Muzzamal Hussain, Ehab M. Mostafa, Ahmed H. El‐Ghorab, Mohammed M. Ghoneim, Samy Selim, Mohamed A. Abdelgawad, Entessar Al Jbawi, Suliman A. Alsagaby, Waleed Al Abdulmonem   +13 more
wiley   +1 more source