Results 61 to 70 of about 332 (146)

Development and optimization of cilostazol loaded transethosomal gel for improved performance

Pharmaceutical Development and Technology
Deep vein thrombosis (DVT) is the third major leading cause of mortality and morbidity after cardiovascular disease and stroke. Cilostazol (CLZ) being one of the antiplatelet agents is effectively used in DVT. However, its oral administration is associated with several problems, such as gastrointestinal side effects and extensive first-pass metabolism.
Midhat, Rehman, Saba, Sohail, Zakir, Ali, Ali H, Alamri, Ahmed A, Lahiq, Taha, Alqahtani, Saleh, Alyahya, Fakhar Ud, Din   +7 more
openaire   +2 more sources

Effect of Edge Activator Combinations in Transethosomal Formulations for Skin Delivery of Thymoquinone via Langmuir Technique

Scientia Pharmaceutica
Thymoquinone (TQ), a bioactive compound found in Nigella sativa seeds, possesses diverse therapeutic properties for skin conditions. However, formulating TQ presents challenges due to its hydrophobic nature and chemical instability, which hinder its skin
Hana Mohd, Katarzyna Dopierała, Anze Zidar, Amitkumar Virani, Bozena Michniak-Kohn   +4 more
doaj   +1 more source

BIFONAZOLE LOADED TRANSETHOSOMAL GEL: FORMULATION AND OPTIMIZATION BY BOX BEHNKEN DESIGN [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
This study was intended to develop and optimize the transethosomal gel of Bifonazole for the treatment of fungal infections. For the optimization purpose, Box-Behnken Design was used, and the concentration of soya lecithin, ethanol and sodium cholate ...
Kshema ., Sandhya Vasanth, Sneh Priya
doaj   +1 more source

Use of transethosomes for enhancing the transdermal delivery of olmesartan medoxomil: in vitro, ex vivo, and in vivo evaluation

International Journal of Nanomedicine, 2019
Rofida Albash,1 Aly A Abdelbary,2,3 Hanan Refai,1 Mohamed A El-Nabarawi2 1Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt; 2Department of Pharmaceutics and ...
Albash R, Abdelbary AA, Refai H, El-Nabarawi MA   +3 more
doaj  

Transethosome-mediated curcumin delivery promotes superior wound healing with reduced toxicity [PDF]

Pharmacia
Background: Curcumin is a natural compound with anti-inflammatory, antimicrobial, and antioxidant effects; however, its clinical use in wound care is restricted by its poor water solubility and low skin absorption.
Meriem Rezigue, Alaa A. A. Aljabali, Walhan Alshaer   +2 more
doaj   +3 more sources

Transethosome Technology: Revolutionizing Transdermal Drug Delivery

Asian Journal of Pharmaceutical Research and Development
In recent years, transdermal drug delivery has become increasingly popular as it overcomes issues with oral administration. The main challenge in this method is the complex stratum corneum barrier that prevents the transdermal administration of drugs.
Sneha R.Patil, Vishveshwar Dharashive, Sameer Shafi, Muktai N. Rudrurkar, Anis J. Kazi, Punam V. Ritthe   +5 more
openaire   +1 more source

Transethosomes in Psoriasis: Mechanisms, Challenges, and Future Directions

Biosciences Biotechnology Research Asia
ABSTRACT: Psoriasis is a chronic relapsing skin disease, which is associated with an immunological reaction of T-cells, resulting in increased activity of keratinocytes and an erythematous-plaque type of lesion covered with silvery-white scaling. The disease concerns 2 – 4% of the total population and exerts severe influence on the patient’s body and ...
Pooja Gajanan Akoshkar, Rahul Dnyaneshwar Khaire, Vikas Dhamu Kunde, Pratiksha Suresh Katkade, Gauravi Sunilrao Kherde, Komal Sunil Taru   +5 more
openaire   +1 more source

Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes

International Journal of Nanomedicine, 2015
Andreia Ascenso,1 Sara Raposo,1 Cátia Batista,2 Pedro Cardoso,2 Tiago Mendes,2 Fabíola Garcia Praça,3 Maria Vitória Lopes Badra Bentley,3 Sandra Simões1 1Instituto de Investigação do Medicamento (iMed ...
Ascenso A, Raposo S, Batista C, Cardoso P, Mendes T, Praça FG, Bentley MVLB, Simões S   +7 more
doaj  

Next-Generation Nanocarriers for Skin Cancer Therapy via Transdermal Delivery

Nano Biomedicine and Engineering
The global burden of cancer, a progressive disease with complex etiology, continues to rise. With an estimated 1.5 million new diagnoses each year, including nearly 350 000 cases of highly aggressive melanoma, the need for improved therapeutic strategies
Bhushan Rane, Nandini Mhatre, Ashish Jain   +2 more
doaj   +1 more source

Study of new age liposomes: transethosomes

, 2020
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openaire   +1 more source