Results 31 to 40 of about 154 (98)

Design and Characterization of a Transethosome‐Based Gel for Cutaneous Administration of Genistein

open access: yesJournal of Nanotechnology
In this study, lipid nanovesicular systems such as ethosome and transethosome dispersions were studied as potential vehicles for the cutaneous administration of genistein, an isoflavone with antioxidant and chemopreventive properties.
Santamaria, Federico   +13 more
openaire   +2 more sources

Allicin-Based Transethosomal Gel: A Novel Herbal Approach for Psoriasis Treatment

open access: yesAsian Journal of Pharmaceutical Research and Development
Allicin, Garlic is the source of allicin, a bioactive organosulfur molecule that has shown strong antibacterial, anti-inflammatory, and immunomodulatory properties, making it a possible topical treatment for psoriasis. However, because of its limited skin penetration and poor aqueous stability, its therapeutic value is limited.
null Yogita K. Kothawade   +2 more
openaire   +1 more source

DEVELOPMENT AND OPTIMIZATIONS OF TRANSETHOSOMAL GEL LOADED WITH RUBIA CORDIFOLIA EXTRACT FOR TREATMENT OF PSORIASIS

open access: yesInternational Journal of Applied Pharmaceutics
Objective: This study aimed to develop and optimize a transethosomal gel loaded with Rubia cordifolia extract to enhance its topical delivery and therapeutic efficacy for the treatment of psoriasis. Methods: A box–behnken factorial design was employed to optimize transethosome formulations using three independent variables: Phospholipon 90 G, sodium ...
POOJA GAJANAN AKOSHKAR   +2 more
openaire   +1 more source

DESIGN, OPTIMIZATION, AND EVALUATION OF A LORNOXICAM-LOADED TRANSETHOSOMAL GEL FOR ENHANCED TRANSDERMAL DELIVERY

open access: yesInternational Journal of Applied Pharmaceutics
Objective: Lornoxicam is an effective oxicam-class non-steroidal anti-inflammatory agent administered in the managing acute & chronic inflammatory conditions. However, its oral administration is inadequate by deprived aqueous solubility, extensive first-pass metabolism, & gastrointestinal adverse effects.
NABAMITA SEN   +2 more
openaire   +1 more source

FORMULATION, SYSTEMATIC OPTIMIZATION, IN VITRO, EX VIVO, AND STABILITY ASSESSMENT OF TRANSETHOSOME BASED GEL OF CURCUMIN

open access: yesAsian Journal of Pharmaceutical and Clinical Research, 2018
Objectives: The current work presents a formulation of curcumin-loaded transethosome (CRM-TE) in the form of a gel and its characterization.Methods: Thirteen formulations were prepared by varying the concentration of Phospholipon 90G as lipid, ethanol, and ratio of lipid: Span using Box- Behnken Design.
Prabhjot Kaur   +12 more
openaire   +2 more sources

Formulation and Evaluation of Allopurinol Loaded Transethosomal Gel

open access: yes
The main aim of this research is formulate allopurinol loaded Transethosomal gel in which Transethosomes of allopurinol were composed of different concentration of soya lecithin, Cholesterol, tween-80 and solvent by using the cold method. Transethosomes were characterized of entrapment efficient, SEM (scanning electron microscopy), FTIR (Fourier ...
openaire   +2 more sources

Preparation of paeoniflorin-glycyrrhizic acid complex transethosome gel and its preventive and therapeutic effects on melasma

open access: yesEuropean Journal of Pharmaceutical Sciences
Paeoniflorin (PF) and glycyrrhizic acid (GL) have skin beautifying effects of anti-inflammation, anti-oxidation, inhibition of melanin formation, and reduction of skin pigmentation. To improve the transdermal permeability of PF and GL in transdermal drug delivery system (TDDS) and enhance their anti-melasma efficacy, PF-GL transethosome (PF-GL-TE) was ...
Yaoyao, Xiao   +8 more
openaire   +2 more sources

Formulation And Evaluation of Tea Tree Oil Infused Transethosomal Gel

open access: yes
Acne vulgaris is a common inflammatory skin disorder that often requires long-term topical therapy; however, conventional formulations are limited by poor skin penetration, instability of active ingredients, and local irritation. Tea tree oil–loaded transethosomal gel can enhance topical anti-acne delivery.
openaire   +2 more sources

Development and Characterization of Tinospora cordifolia extract Loaded Transethosomal Gel for Topical use

open access: yesAsian Journal of Basic Science & Research
The aim of this study was to formulate and evaluate transethosomes containing Tinospora cordifolia for the treatment of arthritis. Tinospora cordifolia, known for its properties, was encapsulated in transethosomes to enhance its bioavailability and therapeutic efficacy.
openaire   +1 more source

Transdermal delivery of lornoxicam via transethosomal gel as a novel strategy for management of rheumatoid arthritis

open access: yesDrug Development and Industrial Pharmacy
This study aimed to develop and optimize lornoxicam-loaded transethosomal vesicles (LOR-TES) to improve the solubility, skin permeation, and transdermal delivery of lornoxicam for potential use in the treatment of rheumatoid arthritis. LOR-TES formulations were prepared using the thin-film hydration method.
Muneer, Ayesha   +11 more
openaire   +1 more source

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