Results 41 to 50 of about 167 (119)

Regulation of mitophagy and mitochondrial function: Natural compounds as potential therapeutic strategies for Parkinson's disease

Phytotherapy Research, Volume 38, Issue 4, Page 1838-1862, April 2024.
Abstract Mitochondrial damage is associated with the development of Parkinson's disease (PD), indicating that mitochondrial‐targeted treatments could hold promise as disease‐modifying approaches for PD. Notably, natural compounds have demonstrated the ability to modulate mitochondrial‐related processes. In this review article, we discussed the possible
Hao Liang, Zhenwang Ma, Wei Zhong, Jia Liu, Kazuo Sugimoto, Hong Chen   +5 more
wiley   +1 more source

Maximizing the Use of Ivermectin Transethosomal Cream in the Treatment of Scabies

Pharmaceutics
In an effort to tackle the skin reactions frequently observed with topical application of ivermectin (IVM), a study was conducted to develop and optimize transethosomes (TESMs) loaded with IVM for scabies treatment. A three-factor, two-level (23) full factorial design was employed.
Mohammad H. Alyami, Hamad S. Alyami, Asmaa M. Abdo, Shereen A. Sabry, Hanan M. El-Nahas, Margrit M. Ayoub   +5 more
openaire   +3 more sources

Effect of Edge Activator Combinations in Transethosomal Formulations for Skin Delivery of Thymoquinone via Langmuir Technique

Scientia Pharmaceutica
Thymoquinone (TQ), a bioactive compound found in Nigella sativa seeds, possesses diverse therapeutic properties for skin conditions. However, formulating TQ presents challenges due to its hydrophobic nature and chemical instability, which hinder its skin
Hana Mohd, Katarzyna Dopierała, Anze Zidar, Amitkumar Virani, Bozena Michniak-Kohn   +4 more
doaj   +1 more source

Formulation and Characterization of Transethosomes for Enhanced Transdermal Delivery of Propranolol Hydrochloride

Micro and Nanosystems, 2020
Objective: The objective of the present work was to develop transethosomes loaded with propranolol hydrochloride using Lipoid S100 as phospholipid, and oleic acid as permeation enhancer and evaluate them for prolonged release effect, in-vitro skin permeation, and in-vivo plasma concentration.
Lalit Kumar, Puneet Utreja
openaire   +1 more source

Development and optimization of cilostazol loaded transethosomal gel for improved performance

Pharmaceutical Development and Technology
Deep vein thrombosis (DVT) is the third major leading cause of mortality and morbidity after cardiovascular disease and stroke. Cilostazol (CLZ) being one of the antiplatelet agents is effectively used in DVT. However, its oral administration is associated with several problems, such as gastrointestinal side effects and extensive first-pass metabolism.
Midhat, Rehman, Saba, Sohail, Zakir, Ali, Ali H, Alamri, Ahmed A, Lahiq, Taha, Alqahtani, Saleh, Alyahya, Fakhar Ud, Din   +7 more
openaire   +2 more sources

Transethosomes in Psoriasis: Mechanisms, Challenges, and Future Directions

Biosciences Biotechnology Research Asia
ABSTRACT: Psoriasis is a chronic relapsing skin disease, which is associated with an immunological reaction of T-cells, resulting in increased activity of keratinocytes and an erythematous-plaque type of lesion covered with silvery-white scaling. The disease concerns 2 – 4% of the total population and exerts severe influence on the patient’s body and ...
Pooja Gajanan Akoshkar, Rahul Dnyaneshwar Khaire, Vikas Dhamu Kunde, Pratiksha Suresh Katkade, Gauravi Sunilrao Kherde, Komal Sunil Taru   +5 more
openaire   +1 more source

Study of new age liposomes: transethosomes

, 2020
99
openaire   +1 more source

Transethosomal Gel for the Topical Delivery of Celecoxib: Formulation and Estimation of Skin Cancer Progression. [PDF]

Pharmaceutics, 2022
Abdellatif AAH, Aldosari BN, Al-Subaiyel A, Alhaddad A, Samman WA, Eleraky NE, Elnaggar MG, Barakat H, Tawfeek HM.   +8 more
europepmc   +1 more source

Design and Characterization of Transethosomes loaded with Rivastigmine for Enhanced Transdermal Delivery

Journal of Research in Pharmacy
This research aimed to create and optimize a transethosomal patch containing Rivastigmine Hydrogen Tartarate, a cholinesterase inhibitor, for the symptomatic management of Alzheimer's disease that would reduce drug loading and patch size. Transethosomes are elastic vesicles made up of phospholipids, ethanol, and edge activator.
Lobo, Cynthia Lizzie, Priya, Sneh
openaire   +2 more sources

Ginger Extract-Loaded Transethosomes for Effective Transdermal Permeation and Anti-Inflammation in Rat Model. [PDF]

Int J Nanomedicine, 2023
Hassan AS, Hofni A, Abourehab MAS, Abdel-Rahman IAM.   +3 more
europepmc   +1 more source