Results 21 to 30 of about 167 (119)

A Rapid Assessment Approach for Skin Stratum-Targeted Drug Delivery Systems Using Mass Spectrometry Imaging and Spatial Clustering. [PDF]

Small Sci
This study presents a novel method for rapidly evaluating dermal drug delivery systems (DDSs). Using mass spectrometry imaging and automated data analysis, it visualizes drug distribution within skin layers in under 10 min. Tested with three nanoscale DDSs for antifungal terbinafine, the approach reveals key differences in drug permeation depth and ...
Yakobi Arancibia R, Bentov-Arava E, Morshin A, Elia J, Natsheh H, Levi-Kalisman Y, Ushki R, Elia A, Touitou E, Margulis K.   +9 more
europepmc   +2 more sources

DIFLUNISAL TRANSETHOSOMES FOR TRANSDERMAL DELIVERY: FORMULATION AND CHARACTERIZATION

International Journal of Applied Pharmaceutics, 2023
Objective: The work aimed to obtain an optimum formula of diflunisal transethosome by varying the types and concentrations of edge activators and optimizing the method of preparations. Methods: Sonication amplitude and sonication time were optimized based on vesicle size and polydispersity index (PDI).
INDAH APRIANTI, null ISKANDARSYAH, HERI SETIAWAN   +2 more
openaire   +1 more source

Ethosomes as Promising Transdermal Delivery Systems of Natural‐Derived Active Compounds

Advanced NanoBiomed Research, Volume 3, Issue 10, October 2023., 2023
Ethosomes are versatile drug delivery systems, particularly suitable for topical applications involving skin barrier penetration. Their high ethanol content strongly improves flexibility and deformability, allowing squeezing through the intercellular spaces without any drug leakage; moreover; ethanol increases the fluidity of the lipids of the cell ...
Melis Emanet, Gianni Ciofani
wiley   +1 more source

Nanotechnology and photodynamic therapy from a clinical perspective

Translational Biophotonics, Volume 5, Issue 1, March 2023., 2023
Photodynamic therapy (PDT) is currently applied clinically in many medical centers worldwide. The clinical outcomes are from one side satisfying and from the other side highlighting the areas of further development. Nanotechnology outstood among the various suggested enhancement solutions.
Sara A. Abdel Gaber, Maha Fadel
wiley   +1 more source

Update on diagnosis and treatment of actinic keratosis

Dermatological Reviews, Volume 3, Issue 6, Page 359-368, December 2022., 2022
Abstract Actinic keratosis (AK) is a relatively common skin condition occurring due to chronic sun‐exposure, primarily affecting fair skin. Most dermatologists consider it an incipient malignancy due to its risk of full‐blown malignant transformation to squamous cell carcinoma.
Komal Agarwal, Indrashis Podder, Clay J. Cockerell, Martin Kassir, Stephan Grabbe, Mohamad Goldust   +5 more
wiley   +1 more source

Drug Delivery (Nano)Platforms for Oral and Dental Applications: Tissue Regeneration, Infection Control, and Cancer Management

Advanced Science, Volume 8, Issue 8, April 21, 2021., 2021
A wide variety of micro/nanoscale platforms are employed for oral and dental applications including tissue regeneration, infection control, and cancer management. Such micro and nanocarriers deliver ions (e.g., fluoride, calcium, strontium), antibiotic, antiviral, antifungal compounds, as well as genes and proteins.
Pooyan Makvandi, Uros Josic, Masoud Delfi, Filippo Pinelli, Vahid Jahed, Emine Kaya, Milad Ashrafizadeh, Atefeh Zarepour, Filippo Rossi, Ali Zarrabi, Tarun Agarwal, Ehsan Nazarzadeh Zare, Matineh Ghomi, Tapas Kumar Maiti, Lorenzo Breschi, Franklin R Tay   +15 more
wiley   +1 more source

Formulation, Development and Evaluation of Ketoprofen Loaded Transethosomes Gel

Journal of Drug Delivery and Therapeutics, 2022
Ketoprofen ([RS]2-[3-benzoylphenyl]-propionic acid) is widely employed as a non-steroidal anti-inflammatory drug (NSAID). Ketoprofen is offered in a variety of forms in the pharmaceutical industry, including coated tablets, capsules, topical gels, transdermal patches, liquid spray, and injection solutions. The purpose of present work was to look at the
Narendra Kumar Joshi, Vivek Gupta
openaire   +2 more sources

Macrophage targeting of nitazoxanide-loaded transethosomal gel in cutaneous leishmaniasis

Royal Society Open Science, 2022
Topical delivery is preferable over systemic delivery for cutaneous leishmaniasis, because of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide (NTZ) has broad-spectrum activity against various parasites and has the potential to avoid drug resistance developed by enzymatic mutations.
Husna Khalid, Sibgha Batool, Fakhar ud Din, Salman Khan, Gul Majid Khan   +4 more
openaire   +3 more sources

BIFONAZOLE LOADED TRANSETHOSOMAL GEL: FORMULATION AND OPTIMIZATION BY BOX BEHNKEN DESIGN [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
This study was intended to develop and optimize the transethosomal gel of Bifonazole for the treatment of fungal infections. For the optimization purpose, Box-Behnken Design was used, and the concentration of soya lecithin, ethanol and sodium cholate ...
Kshema ., Sandhya Vasanth, Sneh Priya
doaj   +1 more source

GLIBENCLAMIDE TRANSETHOSOME PATCH FOR TRANSDERMAL DELIVERY: FORMULATION AND EVALUATIONS

International Journal of Applied Pharmaceutics, 2023
Objective: The glibenclamide transethosome patch is a patch containing glibenclamide encapsulated in nanoparticle-based vesicles that can improve the penetration of the compound into the skin. The research work aims to evaluate glibenclamide transethosome patches using HPMC and PVP as matrix polymers and glibenclamide as a drug model.
NURUL ARFIYANTI YUSUF, MARLINE ABDASSAH, RACHMAT MAULUDIN, ANIS YOHANA CHAERUNISAA   +3 more
openaire   +1 more source