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Mangiferin as New Potential Anti-Cancer Agent and Mangiferin-Integrated Polymer Systems—A Novel Research Direction [PDF]

open access: yesBiomolecules, 2021
For a long time, the pharmaceutical industry focused on natural biologically active molecules due to their unique properties, availability and significantly less side-effects.
Svetlana Morozkina   +2 more
exaly   +6 more sources

Mangiferin for the Management of Liver Diseases: A Review

open access: yesFoods, 2023
The liver is a digestive and metabolic organ, and several factors can induce liver damage, which is a severe threat to human health. As a natural polyphenolic compound, mangiferin belongs to xanthone glucoside and mainly exists in many plants, such as ...
Lisi Li, Yujia Dong, Xifu Liu, Meng Wang
doaj   +4 more sources

From Nature to Nanotechnology: The Bioactivities of Mangiferin Explored [PDF]

open access: yesNanotechnology, Science and Applications
Haitham Al-Madhagi Biochemical Technology Program, Dhamar University, Dhamar, YemenCorrespondence: Haitham Al-Madhagi, Email bio.haitham@tu.edu.yeAbstract: Mangiferin, a naturally occurring C-glucosylxanthone derived from various parts of the mango tree (
Al-Madhagi H
doaj   +4 more sources

Improving Aqueous Solubility of Natural Antioxidant Mangiferin through Glycosylation by Maltogenic Amylase from Parageobacillus galactosidasius DSM 18751

open access: yesAntioxidants, 2021
Mangiferin is a natural antioxidant C-glucosidic xanthone originally isolated from the Mangifera indica (mango) plant. Mangiferin exhibits a wide range of pharmaceutical activities. However, mangiferin’s poor solubility limits its applications.
Jiumn-Yih Wu   +5 more
doaj   +2 more sources

The effect of mangiferin on skin: Penetration, permeation and inhibition of ECM enzymes. [PDF]

open access: yesPLoS ONE, 2017
Mangiferin (2-C-β-D-glucopyranosyl-1,3,6,7-tetrahydroxyxanthone) is a polyphenol with strong antioxidant properties. Mangiferin is obtained from the mango tree (Mangifera indica L., Anacardiaceae).
Renata Ochocka   +4 more
doaj   +2 more sources

Nanocrystals of Mangiferin Using Design Expert: Preparation, Characterization, and Pharmacokinetic Evaluation

open access: yesMolecules, 2023
Making nanoscale drug carriers could boost the bioavailability of medications that are slightly water soluble. One of the most promising approaches for enhancing the chemical stability and bioavailability of a variety of therapeutic medicines is liquid ...
Abdur Rehman Sarwar   +3 more
doaj   +2 more sources

Mangiferin inhibits cGAS-STING pathway-related inflammation via Nrf2 activation to protect against sepsis-induced heart injury [PDF]

open access: yesChinese Medicine
Background Septic cardiomyopathy is characterized by oxidative stress and inflammation, and accounts for its associated high mortality. Mangiferin is a naturally occurring xanthonoid found abundantly in Anemarrhena asphodeloides Bunge, a traditional ...
Junna Song   +6 more
doaj   +2 more sources

Antidiabetic Potential of Mangiferin: An In Silico and In Vivo Approach [PDF]

open access: yesPharmaceutics
Objectives: According to published data, mangiferin has the potential to prevent diabetes mellitus. The aim of this work was to obtain in vivo evidence of the biological activity of mangiferin predicted in silico.
Anna Vesnina   +3 more
doaj   +2 more sources

In-silico and in-vitro studies on the efficacy of mangiferin against colorectal cancer

open access: yesBMC Chemistry, 2022
Background Mangiferin is a C-glycoside xanthone molecule having a wide range of therapeutic properties. Hence, the present study aims to understand the efficacy of mangiferin against colorectal cancer (CRC) and to elucidate the mechanisms of action of ...
Rohini Samadarsi   +3 more
doaj   +1 more source

Mangiferin promotes osteogenic differentiation and alleviates osteoporosis in the ovariectomized mouse via the AXL/ERK5 pathway

open access: yesFrontiers in Pharmacology, 2022
Mangiferin is a xanthone glucoside extracted from multiple plants, which has been shown to inhibit bone resorption and alleviate osteoporosis. However, the effect of purified Mangiferin on osteoporosis and its specific mechanisms is unknown.
Jinwen He   +4 more
doaj   +1 more source

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