Mangiferin: a Promising Anticancer Bioactive [PDF]
Of late, several biologically active antioxidants from natural products have been investigated by the researchers in order to combat the root cause of carcinogenesis, in other words, oxidative stress. Mangiferin, a therapeutically active C-glucosylated xanthone, is extracted from pulp, peel, seed, bark and leaf of Mangifera indica. These polyphenols of
Khurana, Rajneet Kaur +4 more
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Mangiferin and Cancer: Mechanisms of Action [PDF]
Mangiferin, a bioactive compound derived primarily from Anacardiaceae and Gentianaceae families and found in mangoes and honeybush tea, has been extensively studied for its therapeutic properties. Mangiferin has shown promising chemotherapeutic and chemopreventative potential.
Fuchsia Gold-Smith +2 more
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Estrogen modulation properties of mangiferin and quercetin and the mangiferin metabolite norathyriol
Mango fruit contain many bioactive compounds, some of which are transcription factor regulators.
Wilkinson, Ashley S. +8 more
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Mangiferin protects rat myocardial tissue against cyclophosphamide induced cardiotoxicity
Background: Mangiferin is a highly potent antioxidant present in mango leaves which is utilized for therapeutic purposes. Objective: The present study was undertaken to evaluate the cardioprotective effect of mangiferin against cyclophosphamide induced ...
Laxit Bhatt, Binu Sebastian, Viraj Joshi
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Mangiferin prevents guinea pig tracheal contraction via activation of the nitric oxide-cyclic GMP pathway. [PDF]
Previous studies have described the antispasmodic effect of mangiferin, a natural glucoside xanthone (2-C-β-Dgluco-pyranosyl-1,3,6,7-tetrahydroxyxanthone) that is present in mango trees and other plants, but its mechanism of action remains unknown.
Aline B Vieira +6 more
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Abstract Mangiferin, C 19 H 18 O 11 , has been isolated from the leaves, heartwood and stem-bark of Mangifera indica . Its properties indicate that it is a stable C-glycoside of the xanthone group. Reductive hydrolysis with hydriodic acid and oxidation with ferric chloride yield 1,3,6,7-tetrahydroxyxanthone and glucose respectively indicating that ...
V.K. Bhatia +2 more
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Investigation of acute, sub-chronic toxicity, effects of mangiferin and mangiferin solid dispersion (HPTR) on Triton WR1339-induced hyperlipidemia on Swiss albino mice [PDF]
Mangiferin is a xanthonoid found in Mango leaves in abundance with many effects as a hypoglycemic, antioxidant, and anti-inflammatory agent, plant metabolite, and so on. However, nowadays, mango leaves are merely a waste product in Vietnam.
Duyen Thi My Huynh +9 more
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Determination of mangiferin using carbon paste electrode modified with ionic liquid and NiFe2O4 nanoparticles [PDF]
A highly sensitive electrochemical sensor was fabricated based on ionic liquid and NiFe2O4 nanoparticles modified carbon paste electrode for determination of mangiferin.
Hadi Beitollahi, Shohreh Jahani
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Mangiferin induces cell death against rhabdomyosarcoma through sustained oxidative stress
Background: Embryonic rhabdomyosarcoma (RD) is the most prevalent type of cancer among children. The present study aimed to investigate cell death induced by mangiferin in RD cells.
Vishwanadha Vijaya Padma +3 more
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Screening, Characterization and Evaluation of Mangiferin Polymorphs [PDF]
Mangiferin is a compound with many pharmacological activities and exists in many natural products. Anhydrous and hydrate of mangiferin have been reported separately in two literatures, but the polymorphism of this compound has not been realized until ...
Shiying Yang +7 more
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