Results 11 to 20 of about 167 (119)

Design and Characterization of a Transethosome‐Based Gel for Cutaneous Administration of Genistein

Journal of Nanotechnology
In this study, lipid nanovesicular systems such as ethosome and transethosome dispersions were studied as potential vehicles for the cutaneous administration of genistein, an isoflavone with antioxidant and chemopreventive properties.
Federico Santamaria, Ilenia Gugel, Valentyn Dzyhovskyi, Paolo Moretti, Paolo Mariani, Alessia Pepe, Maria Grazia Ortore, Michal Rawski, Anna Baldisserotto, Stefano Manfredini, Alice Casoni, Mascia Benedusi, Giuseppe Valacchi, Elisabetta Esposito   +13 more
exaly   +5 more sources

Exploring the potential of transethosomes in therapeutic delivery: A comprehensive review

MedComm – Biomaterials and Applications, 2023
The growing need for innovative drug delivery systems has led to extensive research to address the limitations associated with conventional dosage forms.
Pavani Chowdary, Ananya Padmakumar, Aravind Kumar Rengan   +2 more
doaj   +3 more sources

Development and Evaluation of Azithromycin-Loaded Transethosomes for Enhanced Dermal Delivery and Antibacterial Efficacy [PDF]

Pharmaceutics
Background/Objectives: The topical delivery of antibiotics through transethosomes shows promise for enhancing its dermal delivery for the treatment of skin infections.
Meriem Rezigue, Hadeia Mashaqbeh, Alaa A. A. Aljabali, Randa SH. Mansour, Iyad Hamzeh   +4 more
doaj   +2 more sources

Enhanced transdermal permeability and drug deposition of rheumatoid arthritis via sinomenine hydrochloride-loaded antioxidant surface transethosome [PDF]

International Journal of Nanomedicine, 2019
Hui Song,1,2 Jin Wen,3 He Li,1,2 Ya Meng,1,2 Yujia Zhang,1,2 Nan Zhang,1,2 Wensheng Zheng1,21State Key Laboratory of Bioactive Substance and Function of Natural Medicines; 2Beijing City Key Laboratory of Drug Delivery Technology and Novel Formulation ...
Song H, Wen J, Li H, Meng Y, Zhang Y, Zhang N, Zheng W   +6 more
doaj   +2 more sources

Nutlin-3 Loaded Ethosomes and Transethosomes to Prevent UV-Associated Skin Damage [PDF]

Life
The skin’s protective mechanisms, in some cases, are not able to counteract the destructive effects induced by UV radiations, resulting in dermatological diseases, as well as skin aging.
Elisabetta Esposito, Francesca Ferrara, Markus Drechsler, Olga Bortolini, Daniele Ragno, Sofia Toldo, Agnese Bondi, Alessandra Pecorelli, Rebecca Voltan, Paola Secchiero, Giorgio Zauli, Giuseppe Valacchi   +11 more
doaj   +2 more sources

Vesicular Drug Delivery Systems: Promising Approaches in Ocular Drug Delivery [PDF]

Pharmaceuticals
Ocular drug delivery poses unique challenges due to the complex anatomical and physiological barriers of the eye. Conventional dosage forms often fail to achieve optimal therapeutic outcomes due to poor bioavailability, short retention time, and off ...
Eslim Batur, Samet Özdemir, Meltem Ezgi Durgun, Yıldız Özsoy   +3 more
doaj   +2 more sources

Mitigation of Rheumatic Arthritis in a Rat Model via Transdermal Delivery of Dapoxetine HCl Amalgamated as a Nanoplatform: In vitro and in vivo Assessment [PDF]

International Journal of Nanomedicine, 2020
Heba Farouk Salem,1 Mohamed Mahmoud Nafady,2 Rasha Mostafa Kharshoum,1 Omnia Ahmed Abd el-Ghafar,3 Hanan Osman Farouk2 1Pharmaceutics and Industrial Pharmacy Department, Faculty of Pharmacy, Beni- Suef University, Beni Suef, Egypt; 2Pharmaceutics and ...
Salem HF, Nafady MM, Kharshoum RM, Abd el-Ghafar OA, Farouk HO   +4 more
doaj   +2 more sources

Transethosome-mediated curcumin delivery promotes superior wound healing with reduced toxicity [PDF]

Pharmacia
Background: Curcumin is a natural compound with anti-inflammatory, antimicrobial, and antioxidant effects; however, its clinical use in wound care is restricted by its poor water solubility and low skin absorption.
Meriem Rezigue, Alaa A A Aljabali, Walhan Alshaer   +2 more
exaly   +4 more sources

IMPROVED SKIN PENETRATION AND DEPOSITION OF NAFTIFINE FROM TRANSETHOSOMES AND TRANSETHOSOMAL GEL FORMULATIONS

FARMACIA, 2022
The main objective of the present study was to develop and characterize naftifine loaded transethosomes and their comparison with marketed cream of naftifine (Exoderil (R), Sandoz Turkiye) for enhanced dermal delivery. Transethosomes loaded with naftifine were developed using the film dispersion method and evaluated for particle size and size ...
Guzel, Imren Esenturk, Gungor, Sevgi, Erdal, Meryem Sedef   +2 more
openaire   +2 more sources

Transethosomal gel for enhancing transdermal delivery of natural therapeutics. [PDF]

Nanomedicine (Lond)
Transethosomes, a fusion of transferosomes and ethosomes, combine the advantageous attributes of both vesicular systems to enhance deformability and skin permeation. While skin delivery is effective for drug transport, overcoming the skin barrier remains a significant challenge, particularly for plant-based products with poor permeability ...
Malang SD, Shambhavi, Sahu AN.
europepmc   +3 more sources