Results 11 to 20 of about 155,620 (276)
Transfer RNA Fragments in the Kidney in Hypertension. [PDF]
Hypertension, 2021 Small noncoding RNAs (sncRNAs) are important regulators of gene expression. In contrast with well-studied microRNAs, transfer RNA-derived RNA fragments (tRFs) are a new class of sncRNAs that has not been studied in hypertension. This study aims to characterize renal tRFs and identify dysregulation and potential role of renal tRFs in ...
Pan X +8 more
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Editorial: The genome’s rising star: Transfer RNA-derived small fragments [PDF]
Frontiers in Molecular Biosciences, 2022 Wei Yan
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tRFdb: a database for transfer RNA fragments. [PDF]
Nucleic Acids Res, 2015 We have created tRFdb, the first database of transfer RNA fragments (tRFs), available at http://genome.bioch.virginia.edu/trfdb/. With over 100 small RNA libraries analyzed, the database currently contains the sequences and read counts of the three classes of tRFs for eight species: R. sphaeroides, S. pombe, D. melanogaster, C.
Kumar P, Mudunuri SB, Anaya J, Dutta A.
europepmc +5 more sources
Pre-symptomatic Parkinson's disease blood test quantifying repetitive sequence motifs in transfer RNA fragments. [PDF]
Nat AgingEarly, efficient Parkinson's disease (PD) tests may facilitate pre-symptomatic diagnosis and disease-modifying therapies. Here we report elevated levels of PD-specific transfer RNA fragments carrying a conserved sequence motif (RGTTCRA-tRFs) in the substantia nigra, cerebrospinal fluid and blood of patients with PD.
Madrer N +11 more
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Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases [PDF]
Genomics & Informatics, 2015 tRNA-derived RNA fragments (tRFs) are an emerging class of non-coding RNAs (ncRNAs). A growing number of reports have shown that tRFs are not random degradation products but are functional ncRNAs made of specific tRNA cleavage. They play regulatory roles
Yu Fu +3 more
doaj +3 more sources
Transfer
New Phytologist, 2023 SummaryAccording to current textbooks, the principal task of transfer and ribosomal RNAs (tRNAs and rRNAs, respectively) is synthesizing proteins. During the last decade, additional cellular roles for precisely processed tRNA and rRNAs fragments have become evident in all kingdoms of life. These RNA fragments were originally overlooked in transcriptome
Ralph Panstruga, Pietro D. Spanu
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ASSOCIATION BETWEEN TRANSFER RNA-DERIVED FRAGMENTS AND VARICOCELE [PDF]
Fertility and Sterility, 2023 Öz bulunamadı.
Asli Metin Mahmutoglu +4 more
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tRFtarget: a database for transfer RNA-derived fragment targets [PDF]
Nucleic Acids Research, 2020 AbstractTransfer RNA-derived fragments (tRFs) are a new class of small non-coding RNAs and play important roles in biological and physiological processes. Prediction of tRF target genes and binding sites is crucial in understanding the biological functions of tRFs in the molecular mechanisms of human diseases.
Ningshan Li +3 more
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PtRFdb: a database for plant transfer RNA-derived fragments [PDF]
Database, 2018 Transfer RNA-derived fragments (tRFs) represent a novel class of small RNAs (sRNAs) generated through endonucleolytic cleavage of both mature and precursor transfer RNAs (tRNAs). These 14-28 nt length tRFs that have been extensively studied in animal kingdom are to be explored in plants. In this study, we introduce a database of plant tRFs named PtRFdb
Nikita Gupta +3 more
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Emerging roles of transfer RNA fragments in the CNS. [PDF]
BrainAbstract Transfer RNA-derived small RNAs (tsRNAs), previously considered inactive tRNA degradation products, have now been shown to be functional small non-coding RNAs. They may play important roles within the CNS and in brain-body interactions, both during normal developmental stages as well as in diverse brain pathologies.
Winek K, Soreq H.
europepmc +4 more sources